胰头切除后发生并发症的危险因素
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文题： Risk factors for complications after pancreatic head resection.
作者： Adam U, Makowiec F, Riediger H, Schareck WD, Benz S, Hopt UT.
杂志全名： American journal of surgery.
年份，卷（期）: 起止页码： 2004 Feb;187(2):201-8.
PMID: 14769305
英文摘要：BACKGROUND: Postoperative morbidity is high after pancreatic head resections. Data about risk factors are controversial. The aim of this study was to evaluate risk factors for complications after pancreatic head resection and to assess whether the complication rate changed during the study period. METHODS: Data of 301 patients undergoing pancreatic head resection were recorded prospectively. Risk factors were assessed by multivariate analysis. The first and second part of the study period were compared. RESULTS: Mortality was 3%. Overall and surgery-related complications occurred in 42% and 28%, respectively. Independent risk factors for postoperative morbidity were impaired renal function (odds ratio [OR] 2.7), absence of preoperative biliary drainage (OR 1.9), and resection of other organs (OR 3.2). Complication rate, duration of surgery, amount of blood transfused, and length of hospital stay decreased during the study period. CONCLUSIONS: Increasing hospital experience decreased complication rates. Patients with risk factors should be considered for transferal to specialized centers.
中文译文：胰头切除后发生并发症的危险因素
背景：胰头切除后发生并发症的比例较高。关于发生并发症的危险因素各家报道不一致，仍有争议。本研究旨在评价胰头切除后发生并发症的危险因素并试图了解在研究期间并发症的发病率是否会发生变化。
方法：对301名行胰头切除术的患者进行前瞻性分析。运用多变量分析评价危险因素。对研究的第一和第二阶段进行对比。
结果： 死亡率为3%，总并发症率和外科手术导致的并发症率分别为42%和28%，发生并发症的独立危险因素为肾功能损害(优势比[OR]：2.7),术前未行胆道引流(OR 1.9),其它脏器曾行切除术(OR 3.2)。并发症的发生率、手术所需时间、所需输血量、住院天数在研究期间呈下降趋势。
结论：患者所处的医院处理该类疾病的经验丰富可降低并发症发生率，因此若患者存在上述危险因素，应转到专科中心进行处理。
版权声明：本译文文字内容版权归丁香园网站（ http://www.dxy.cn ）所有，未经本网站书面许可，请勿转载或摘编。
作者： Adam U, Makowiec F, Riediger H, Schareck WD, Benz S, Hopt UT.
杂志全名： American journal of surgery.
年份，卷（期）: 起止页码： 2004 Feb;187(2):201-8.
PMID: 14769305
英文摘要：BACKGROUND: Postoperative morbidity is high after pancreatic head resections. Data about risk factors are controversial. The aim of this study was to evaluate risk factors for complications after pancreatic head resection and to assess whether the complication rate changed during the study period. METHODS: Data of 301 patients undergoing pancreatic head resection were recorded prospectively. Risk factors were assessed by multivariate analysis. The first and second part of the study period were compared. RESULTS: Mortality was 3%. Overall and surgery-related complications occurred in 42% and 28%, respectively. Independent risk factors for postoperative morbidity were impaired renal function (odds ratio [OR] 2.7), absence of preoperative biliary drainage (OR 1.9), and resection of other organs (OR 3.2). Complication rate, duration of surgery, amount of blood transfused, and length of hospital stay decreased during the study period. CONCLUSIONS: Increasing hospital experience decreased complication rates. Patients with risk factors should be considered for transferal to specialized centers.
中文译文：胰头切除后发生并发症的危险因素
背景：胰头切除后发生并发症的比例较高。关于发生并发症的危险因素各家报道不一致，仍有争议。本研究旨在评价胰头切除后发生并发症的危险因素并试图了解在研究期间并发症的发病率是否会发生变化。
方法：对301名行胰头切除术的患者进行前瞻性分析。运用多变量分析评价危险因素。对研究的第一和第二阶段进行对比。
结果： 死亡率为3%，总并发症率和外科手术导致的并发症率分别为42%和28%，发生并发症的独立危险因素为肾功能损害(优势比[OR]：2.7),术前未行胆道引流(OR 1.9),其它脏器曾行切除术(OR 3.2)。并发症的发生率、手术所需时间、所需输血量、住院天数在研究期间呈下降趋势。
结论：患者所处的医院处理该类疾病的经验丰富可降低并发症发生率，因此若患者存在上述危险因素，应转到专科中心进行处理。
版权声明：本译文文字内容版权归丁香园网站（ http://www.dxy.cn ）所有，未经本网站书面许可，请勿转载或摘编。
