《结直肠疾病》Dis Colon Rectum 2022年第4期临床实践指南参考文献

Diseases of the Colon & Rectum (《结直肠疾病》)是美国结直肠外科医师协会（ASCRS）官方期刊，在威科医疗（Wolters Kluwer Health）旗下Lippincott平台出版。DC&R是公认的结肠、直肠和肛门疾病研究的权威期刊，出版原创研究、综述、简短通讯等文章。50多年来，DC&R一直是结直肠外科医生和胃肠病学家在此专业领域中交流与传播外科医学知识和信息的首选杂志。

UpToDate临床顾问【DC&R专区】定期分享DC&R杂志文章的中文翻译版，本文为2022年第4期临床实践指南。

接上一篇，参考文献如下

11. Guyatt G, Gutterman D, Baumann MH, et al. Grading strength of recommendations and quality of evidence in clinical guidelines: report from an American College Of Chest Physicians Task Force. Chest. 2006;129:174–181.

12. Reissman P, Agachan F, Wexner SJTAS. Outcome of laparoscopic colorectal surgery in older patients. 1996;62:1060-3.

13. Baek S-J, Kim S-H, Kim S-Y, Shin J-W, Kwak J-M, Kim JJSe. The safety of a “fast-track” program after laparoscopic colorectal surgery is comparable in older patients as in younger patients. 2013;27:1225-32.

14. Schwandner O, Schiedeck TH, Bruch H-PJDotc, rectum. Advanced age—indication or contraindication for laparoscopic colorectal surgery? 1999;42:356-62.

15. Forsmo HM, Erichsen C, Rasdal A, Körner H, Pfeffer FJG, Medicine G. Enhanced recovery after colorectal surgery (ERAS) in elderly patients is feasible and achieves similar results as in younger patients. 2017;3:2333721417706299.

16. Vironen JH, Sainio P, Husa AI, Kellokumpu IHJDotc, rectum. Complications and survival after surgery for rectal cancer in patients younger than and aged 75 years or older. 2004;47:1225-31.

17. Spivak H, Maele DV, Friedman I, Nussbaum MJJotACoS. Colorectal surgery in octogenarians. 1996;183:46-50.

18. Hamel MB, Henderson WG, Khuri SF, Daley JJJotAGS. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. 2005;53:424-9.

19. Simmonds P, Best L, George S, et al; Colorectal Cancer Collaborative Group. Surgery for colorectal cancer in elderly patients: a systematic review. Lancet. 2000;356:968–974.

20. Shahrokni A, Alexander KJAoso. The age of talking about age alone is over. 2019;26:12-4.

21. Rostoft S, O’Donovan A, Soubeyran P, Alibhai SMH, Hamaker ME. Geriatric assessment and management in cancer. J Clin Oncol. 2021;39:2058–2067.

22. van Walree IC, Scheepers E, van Huis-Tanja L, et al. A systematic review on the association of the G8 with geriatric assessment, prognosis and course of treatment in older patients with cancer. J Geriatr Oncol. 2019;10:847–858.

23. Huisman MG, Audisio RA, Ugolini G, et al. Screening for predictors of adverse outcome in onco-geriatric surgical patients: A multicenter prospective cohort study. Eur J Surg Oncol. 2015;41:844–851.

24. Bessems SAM, Konsten JLM, Vogelaar JFJ, et al. Frailty screening by Geriatric-8 and 4-meter gait speed test is feasible and predicts postoperative complications in elderly colorectal cancer patients. J Geriatr Oncol. 2021;12:592–598.

25. Moriello C, Mayo NE, Feldman L, Carli F. Validating the six-minute walk test as a measure of recovery after elective colon resection surgery. Arch Phys Med Rehabil. 2008;89:1083–1089.

26. George EL, Hall DE, Youk A, et al. Association between patient frailty and postoperative mortality across multiple noncardiac surgical specialties. JAMA Surg. 2021;156:e205152.

27. Al-Khamis A, Warner C, Park J, et al. Modified frailty index predicts early outcomes after colorectal surgery: an ACS-NSQIP study. Colorectal Dis. 2019;21:1192–1205.

28. Pata G, Bianchetti L, Rota M, et al. Multidimensional Prognostic Index (MPI) score has the major impact on outcome prediction in elderly surgical patients with colorectal cancer: the FRAGIS study. J Surg Oncol. 2021;123:667–675.

29. Feng MA, McMillan DT, Crowell K, Muss H, Nielsen ME, Smith AB. Geriatric assessment in surgical oncology: a systematic review. J Surg Res. 2015;193:265–272.

30. Eamer G, Taheri A, Chen SS, et al. Comprehensive geriatric assessment for older people admitted to a surgical service. Cochrane Database Syst Rev. 2018;1:CD012485.

31. Shahrokni A, Vishnevsky BM, Jang B, et al. Geriatric assessment, not ASA physical status, is associated with 6-month postoperative survival in patients with cancer aged ≥ 75 years. J Natl Compr Canc Netw. 2019;17:687–694.

32. Tatar C, Benlice C, Delaney CP, et al. Modified frailty index predicts high-risk patients for readmission after colorectal surgery for cancer. Am J Surg. 2020;220:187–190.

33. National Institutes of Health Consensus Development Conference Statement: geriatric assessment methods for clinical decision-making. J Am Geriatr Soc. 1988;36:342–347.

34. Puts MTE, Alibhai SMH. Fighting back against the dilution of the Comprehensive Geriatric Assessment. J Geriatr Oncol. 2018;9:3–5.

35. Shahrokni A, Alexander K, Wildes TM, Puts MTE. Preventing treatment-related functional decline: strategies to maximize resilience. Am Soc Clin Oncol Educ Book. 2018;38:415–431.

36. Audisio RA, Pope D, Ramesh HS, et al; PACE participants. Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study. Crit Rev Oncol Hematol. 2008;65:156–163.

37. Katlic MR, Coleman J, Khan K, Wozniak SE, Abraham JH. Sinai abbreviated geriatric evaluation: development and validation of a practical test. Ann Surg. 2019;269:177–183.

38. Huisman MG, van Leeuwen BL, Ugolini G, et al. “Timed up & go”: a screening tool for predicting 30-day morbidity in onco-geriatric surgical patients? A multicenter cohort study. PLoS One. 2014;9:e86863.

39. Jones TS, Dunn CL, Wu DS, Cleveland JC Jr, Kile D, Robinson TN. Relationship between asking an older adult about falls and surgical outcomes. JAMA Surg. 2013;148:1132–1138.

40. Hall DE, Arya S, Schmid KK, et al. Development and initial validation of the risk analysis index for measuring frailty in surgical populations. JAMA Surg. 2017;152:175–182.

41. Hall DE, Arya S, Schmid KK, et al. Association of a frailty screening initiative with postoperative survival at 30, 180, and 365 days. JAMA Surg. 2017;152:233–240.

42. Dirks RC, Edwards BL, Tong E, et al. Sarcopenia in emergency abdominal surgery. J Surg Res. 2017;207:13–21.

43. van der Windt DJ, Bou-Samra P, Dadashzadeh ER, Chen X, Varley PR, Tsung A. Preoperative risk analysis index for frailty predicts short-term outcomes after hepatopancreatobiliary surgery. HPB (Oxford). 2018;20:1181–1188.

44. Keller DS, Bankwitz B, Nobel T, Delaney CP. Using frailty to predict who will fail early discharge after laparoscopic colorectal surgery with an established recovery pathway. Dis Colon Rectum. 2014;57:337–342.

45. Panayi AC, Orkaby AR, Sakthivel D, et al. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2019;218:393–400.

46. Wahl TS, Graham LA, Hawn MT, et al. Association of the modified frailty index with 30-day surgical readmission. JAMA Surg. 2017;152:749–757.

47. Shah R, Attwood K, Arya S, et al. Association of frailty with failure to rescue after low-risk and high-risk inpatient surgery. JAMA Surg. 2018;153:e180214.

48. Cruz-Jentoft AJBG, Bahat G, Bauer J, et al; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48:16–31.

49. Abdullahi YS, Athanasopoulos LV, Casula RP, et al. Systematic review on the predictive ability of frailty assessment measures in cardiac surgery. Interact Cardiovasc Thorac Surg. 2017;24:619–624.

50. Heard RSM, Ramsay G, Hildebrand DR. Sarcopaenia in surgical populations: A review. The surgeon: journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 2017;15:366-71.

51. Reisinger KW, van Vugt JL, Tegels JJ, et al. Functional compromise reflected by sarcopenia, frailty, and nutritional depletion predicts adverse postoperative outcome after colorectal cancer surgery. Ann Surg. 2015;261:345–352.

52. Levolger S, van Vugt JL, de Bruin RW, IJzermans JN. Systematic review of sarcopenia in patients operated on for gastrointestinal and hepatopancreatobiliary malignancies. Br J Surg. 2015;102:1448–1458.

53. Zattoni D, Montroni I, Saur NM, et al. A Simple screening tool to predict outcomes in older adults undergoing emergency general surgery. J Am Geriatr Soc. 2019;67:309–316.

54. Payton P, Shook JE. Perioperative understanding of geriatric patients. Clin Podiatr Med Surg. 2019;36:131–140.

55. Kumar C, Salzman B, Colburn JL. Preoperative assessment in older adults: a comprehensive approach. Am Fam Physician. 2018;98:214–220.

56. Schamp R, Tenkku L. Managed death in a PACE: pathways in present and advance directives. J Am Med Dir Assoc. 2006;7:339–344.

57. Bettelli G. Preoperative evaluation of the elderly surgical patient and anesthesia challenges in the XXI century. Aging Clin Exp Res. 2018;30:229–235.

58. Fried TRBE, Bradley EH, Towle VR, Allore H. Understanding the treatment preferences of seriously ill patients. N Engl J Med. 2002;346:1061–1066.

59. Schulte PJ, Roberts RO, Knopman DS, et al. Association between exposure to anaesthesia and surgery and long-term cognitive trajectories in older adults: report from the Mayo Clinic Study of Aging. Br J Anaesth. 2018;121:398–405.

60. Cooper Z, Koritsanszky LA, Cauley CE, et al. Recommendations for best communication practices to facilitate goal-concordant care for seriously ill older patients with emergency surgical conditions. Ann Surg. 2016;263:1–6.

61. Vilches-Moraga A, Fox J. Geriatricians and the older emergency general surgical patient: proactive assessment and patient centred interventions. Salford-POP-GS. Aging Clin Exp Res. 2018;30:277–282.

62. Desserud KF, Veen T, Søreide K. Emergency general surgery in the geriatric patient. Br J Surg. 2016;103:e52–e61.

63. Plassman BL, Langa KM, Fisher GG, et al. Prevalence of dementia in the United States: the aging, demographics, and memory study. Neuroepidemiology. 2007;29:125–132.

64. Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008;148:427–434.

65. Chow WB, Rosenthal RA, Merkow RP, Ko CY, Esnaola NF; American College of Surgeons National Surgical Quality Improvement Program; American Geriatrics Society. Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg. 2012;215:453–466.

66. Borson S, Scanlan JM, Chen P, Ganguli M. The Mini-Cog as a screen for dementia: validation in a population-based sample. J Am Geriatr Soc. 2003;51:1451–1454.

67. Luan Erfe BM, Erfe JM, Brovman EY, Boehme J, Bader AM, Urman RD. Postoperative outcomes in SAVR/TAVR patients with cognitive impairment: a systematic review. Semin Thorac Cardiovasc Surg. 2019;31:370–380.

68. Watt J, Tricco AC, Talbot-Hamon C, et al. Identifying older adults at risk of delirium following elective surgery: a systematic review and meta-analysis. J Gen Intern Med. 2018;33:500–509.

69. Inouye SK, Bogardus ST Jr, Charpentier PA, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med. 1999;340:669–676.

70. American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults. Postoperative delirium in older adults: best practice statement from the American Geriatrics Society. J Am Coll Surg. 2015;220:136–48.e1.

71. American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults. American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adults. J Am Geriatr Soc. 2015;63:142–150.

72. Fields LM, Calvert JD. Informed consent procedures with cognitively impaired patients: A review of ethics and best practices. Psychiatry Clin Neurosci. 2015;69:462–471.

73. Culley DJ, Flaherty D, Fahey MC, et al. Poor performance on a preoperative cognitive screening test predicts postoperative complications in older orthopedic surgical patients. Anesthesiology. 2017;127:765–774.

74. Montroni I, Rostoft S, Spinelli A, et al; SIOG surgical task force/ESSO GOSAFE study group. GOSAFE - Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery: early analysis on 977 patients. J Geriatr Oncol. 2020;11:244–255.

75. Scharre DW, Chang SI, Murden RA, et al. Self-administered Gerocognitive Examination (SAGE): a brief cognitive assessment Instrument for mild cognitive impairment (MCI) and early dementia. Alzheimer Dis Assoc Disord. 2010;24:64–71.

76. Scharre DW, Chang SI, Nagaraja HN, Vrettos NE, Bornstein RA. Digitally translated Self-Administered Gerocognitive Examination (eSAGE): relationship with its validated paper version, neuropsychological evaluations, and clinical assessments. Alzheimers Res Ther. 2017;9:44.

77. Mohanty SR, Rosenthal RA, Russell MM, et al. Optimal perioperative management of the geriatric surgical patient: a best practices guideline from the American College of Surgeons NSQIP and the American Geriatrics Society. J Am Coll Surgeons. 2016;222:930-947.

78. Inouye SK. Joining forces against delirium - from organ-system care to whole-human care. N Engl J Med. 2020;382:499–501.

79. Leslie DL, Marcantonio ER, Zhang Y, Leo-Summers L, Inouye SK. One-year health care costs associated with delirium in the elderly population. Arch Intern Med. 2008;168:27–32.

80. McCusker J, Cole M, Dendukuri N, Belzile E, Primeau F. Delirium in older medical inpatients and subsequent cognitive and functional status: a prospective study. CMAJ. 2001;165:575–583.

81. Inouye SK, Rushing JT, Foreman MD, Palmer RM, Pompei P. Does delirium contribute to poor hospital outcomes? A three-site epidemiologic study. J Gen Intern Med. 1998;13:234–242.

82. O’Keeffe S, Lavan J. The prognostic significance of delirium in older hospital patients. J Am Geriatr Soc. 1997;45:174–178.

83. Hshieh TT, Yue J, Oh E, et al. Effectiveness of multicomponent nonpharmacological delirium interventions: a meta-analysis. JAMA Intern Med. 2015;175:512–520.

84. Robinson TN, Raeburn CD, Tran ZV, Angles EM, Brenner LA, Moss M. Postoperative delirium in the elderly: risk factors and outcomes. Ann Surg. 2009;249:173–178.

85. Marcantonio ER, Goldman L, Mangione CM, et al. A clinical prediction rule for delirium after elective noncardiac surgery. JAMA. 1994;271:134–139.

86. Rostoft S, Hamaker ME. Basic geriatric principles for colorectal surgeons: how to optimize assessment and care of older patients in the perioperative period. Eur J Surg Oncol. 2020;46:310–315.

87. Neufeld KJ, Thomas C. Delirium: definition, epidemiology, and diagnosis. J Clin Neurophysiol. 2013;30:438–442.

88. Siddiqi N HJ, Clegg A, Teale EA, Young J, Taylor J, Simpkins SA. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev 2016 3:CD005563.

89. Shi C, Jin J, Qiao L, Li T, Ma J, Ma Z. Effect of perioperative administration of dexmedetomidine on delirium after cardiac surgery in elderly patients: a double-blinded, multi-center, randomized study. Clin Interv Aging. 2019;14:571–575.

90. Panel AGSBCUE; By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67:674–694.

91. Minnella EM, Carli F. Prehabilitation and functional recovery for colorectal cancer patients. Eur J Surg Oncol. 2018;44:919–926.

92. Waite I, Deshpande R, Baghai M, Massey T, Wendler O, Greenwood S. Home-based preoperative rehabilitation (prehab) to improve physical function and reduce hospital length of stay for frail patients undergoing coronary artery bypass graft and valve surgery. J Cardiothorac Surg. 2017;12:91.

93. Chia CLKMS, Mantoo SK, Tan KY. ‘Start to finish trans-institutional transdisciplinary care’: a novel approach improves colorectal surgical results in frail elderly patients. Colorectal Dis. 2016;18:O43–O50.

94. Mazzola M, Bertoglio C, Boniardi M, et al. Frailty in major oncologic surgery of upper gastrointestinal tract: how to improve postoperative outcomes. Eur J Surg Oncol. 2017;43:1566–1571.

95. Hoogeboom TJ, Dronkers JJ, van den Ende CH, Oosting E, van Meeteren NL. Preoperative therapeutic exercise in frail elderly scheduled for total hip replacement: a randomized pilot trial. Clin Rehabil. 2010;24:901–910.

96. Oosting E, Jans MP, Dronkers JJ, et al. Preoperative home-based physical therapy versus usual care to improve functional health of frail older adults scheduled for elective total hip arthroplasty: a pilot randomized controlled trial. Arch Phys Med Rehabil. 2012;93:610–616.

97. Kamarajah SK, Bundred J, Weblin J, Tan BHL. Critical appraisal on the impact of preoperative rehabilitation and outcomes after major abdominal and cardiothoracic surgery: A systematic review and meta-analysis. Surgery. 2020;167:540–549.

98. Saur NM, Montroni I, Shahrokni A, et al. Care of the geriatric colorectal surgical patient and framework for creating a geriatric program: a compendium from the 2019 American Society of Colon and Rectal Surgeons Annual Meeting. Dis Colon Rectum. 2020;63:1489–1495.

99. Montroni I, Saur NM, Shahrokni A, Suwanabol PA, Chesney TR. Surgical considerations for older adults with cancer: a multidimensional, multiphase pathway to improve care. J Clin Oncol. 2021;39:2090–2101.

100. Carmichael JC, Keller DS, Baldini G, et al. Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons. Dis Colon Rectum. 2017;60:761–784.

101. Carli F, Bessissow A, Awasthi R, Liberman S. Prehabilitation: finally utilizing frailty screening data. Eur J Surg Oncol. 2020;46:321–325.

102. Hedrick TL, Hassinger TE, Myers E, et al. Wearable technology in the perioperative period: predicting risk of postoperative complications in patients undergoing elective colorectal surgery. Dis Colon Rectum. 2020;63:538–544.

103. Hamaker ME, Oosterlaan F, van Huis LH, Thielen N, Vondeling A, van den Bos F. Nutritional status and interventions for patients with cancer - a systematic review. J Geriatr Oncol. 2021;12:6-21.

104. Kamel HK. Sarcopenia and aging. Nutr Rev. 2003;61:157–167.

105. Hargreaves M. Pre-exercise nutritional strategies: effects on metabolism and performance. Can J Appl Physiol. 2001;26(suppl):S64–S70.

106. Leung JM, Sands LP, Mullen EA, Wang Y, Vaurio L. Are preoperative depressive symptoms associated with postoperative delirium in geriatric surgical patients? J Gerontol A Biol Sci Med Sci. 2005;60:1563–1568.

107. Kristjansson JM Sr, Nesbakken A, Skovlund E, Bakka A, Johannessen H, Wyller TB. Which elements of a comprehensive geriatric assessment (CGA) predict post-operative complications and early mortality after colorectal cancer surgery? J Geriatr Oncol. 2010;1:57–65.

108. Parker PA, Pettaway CA, Babaian RJ, et al. The effects of a presurgical stress management intervention for men with prostate cancer undergoing radical prostatectomy. J Clin Oncol. 2009;27:3169–3176.

109. Carli F, Bousquet-Dion G, Awasthi R, et al. Effect of multimodal prehabilitation vs postoperative rehabilitation on 30-day postoperative complications for frail patients undergoing resection of colorectal cancer: a randomized clinical trial. JAMA Surg. 2020;155:233–242.

110. Gillis C, Fenton TR, Gramlich L, et al. Older frail prehabilitated patients who cannot attain a 400 m 6-min walking distance before colorectal surgery suffer more postoperative complications. Eur J Surg Oncol. 2021;47:874–881.

111. Howard R, Yin YS, McCandless L, Wang S, Englesbe M, Machado-Aranda D. Taking control of your surgery: impact of a prehabilitation program on major abdominal surgery. J Am Coll Surg. 2019;228:72–80.

112. Barberan-Garcia A, Ubre M, Pascual-Argente N, et al. Post-discharge impact and cost-consequence analysis of prehabilitation in high-risk patients undergoing major abdominal surgery: secondary results from a randomised controlled trial. Br J Anaesth. 2019;123:450–456.

113. Ghignone F, van Leeuwen BL, Montroni I, et al; International Society of Geriatric Oncology (SIOG) Surgical Task Force. The assessment and management of older cancer patients: A SIOG surgical task force survey on surgeons’ attitudes. Eur J Surg Oncol. 2016;42:297–302. EJSO.

114. Williams GRWK, Weaver KE, Lesser GJ, et al. Capacity to provide geriatric specialty care for older adults in community oncology practices. Oncologist. 2020;25:1032–1038.

115. Shahrokni A, Tin AL, Sarraf S, et al. Association of geriatric comanagement and 90-day postoperative mortality among patients aged 75 years and older with cancer. JAMA Netw Open. 2020;3:e209265.

116. Tarazona-Santabalbina FJ, Llabata-Broseta J, Belenguer-Varea Á, Álvarez-Martínez D, Cuesta-Peredo D, Avellana-Zaragoza JA. A daily multidisciplinary assessment of older adults undergoing elective colorectal cancer surgery is associated with reduced delirium and geriatric syndromes. J Geriatr Oncol. 2019;10:298–303.

117. Van Grootven B, Mendelson DA, Deschodt M. Impact of geriatric co-management programmes on outcomes in older surgical patients: update of recent evidence. Curr Opin Anaesthesiol. 2020;33:114-121.

118. Adogwa O, Elsamadicy AA, Vuong VD, et al. Geriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience: Presented at the 2017 AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves. 2017;27:670-5.

119. Hornor MA, Tang VL, Berian J, et al. Optimizing the feasibility and scalability of a geriatric surgery quality improvement initiative. 2019;67:1074-8.

120. American College of Surgeons Geriatric Surgery Verification Program. https://www.facs.org/quality-programs/geriatric-surgery ; accessed October 18.

121. Berian JR Jr, Rosenthal RA, Baker TL, et al. Hospital standards to promote optimal surgical care of the older adult: a report from the coalition for quality in geriatric surgery. Ann Surg. 2018;267:280–290.

122. Trépanier M, Minnella EM, Paradis T, et al. Improved disease-free survival after prehabilitation for colorectal cancer surgery. Ann Surg. 2019;270:493–501.

123. Gardner B, Jovicic A, Belk C, et al. Specifying the content of home-based health behaviour change interventions for older people with frailty or at risk of frailty: an exploratory systematic review. BMJ Open. 2017;7:e014127.

124. Gale CR, Westbury L, Cooper C. Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing. Age Ageing. 2018;47:392–397.

125. Bunt S, Steverink N, Olthof J, van der Schans CP, Hobbelen JSM. Social frailty in older adults: a scoping review. Eur J Ageing. 2017;14:323–334.

126. Dent E, Morley JE, Cruz-Jentoft AJ, et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23:771–787.

127. Hawkins AT, Pallangyo AJ, Herman AM, et al. The effect of social integration on outcomes after major lower extremity amputation. J Vasc Surg. 2016;63:154–162.

128. Gonzalez-Saenz de Tejada M, Bilbao A, Baré M, et al. Association of social support, functional status, and psychological variables with changes in health-related quality of life outcomes in patients with colorectal cancer. Psychooncology. 2016;25:891–897.

129. Bagnall NM, Malietzis G, Kennedy RH, Athanasiou T, Faiz O, Darzi A. A systematic review of enhanced recovery care after colorectal surgery in elderly patients. Colorectal Dis. 2014;16:947–956.

130. Launay-Savary MV, Mathonnet M, Theissen A, Ostermann S, Raynaud-Simon A, Slim K; GRACE (Groupe francophone de Réhabilitation Améliorée après Chirurgie). Are enhanced recovery programs in colorectal surgery feasible and useful in the elderly? A systematic review of the literature. J Visc Surg. 2017;154:29–35.

131. Holubar SD, Hedrick T, Gupta R, et al; Perioperative Quality Initiative (POQI) I Workgroup. American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on prevention of postoperative infection within an enhanced recovery pathway for elective colorectal surgery. Perioper Med (Lond). 2017;6:4.

132. Migaly J, Bafford AC, Francone TD, et al; Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the use of bowel preparation in elective colon and rectal surgery. Dis Colon Rectum. 2019;62:3–8.

133. Fleet JL, Dixon SN, Kuwornu PJ, et al. Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study. PLoS One. 2018;13:e0193134.

134. Tejedor P, Pastor C, Gonzalez-Ayora S, Ortega-Lopez M, Guadalajara H, Garcia-Olmo D. Short-term outcomes and benefits of ERAS program in elderly patients undergoing colorectal surgery: a case-matched study compared to conventional care. Int J Colorectal Dis. 2018;33:1251–1258.

135. Gonzalez-Ayora S, Pastor C, Guadalajara H, et al. Enhanced recovery care after colorectal surgery in elderly patients. Compliance and outcomes of a multicenter study from the Spanish working group on ERAS. Int J Colorectal Dis. 2016;31:1625–1631.

136. Wang Q, Suo J, Jiang J, Wang C, Zhao YQ, Cao X. Effectiveness of fast-track rehabilitation vs conventional care in laparoscopic colorectal resection for elderly patients: a randomized trial. Colorectal Dis. 2012;14:1009–1013.

137. Forsmo HM, Erichsen C, Rasdal A, Körner H, Pfeffer F. Enhanced recovery after colorectal surgery (ERAS) in elderly patients is feasible and achieves similar results as in younger patients. Gerontol Geriatr Med. 2017;3:2333721417706299. 10.1177/2333721417706299

138. Jia Y, Jin G, Guo S, et al. Fast-track surgery decreases the incidence of postoperative delirium and other complications in elderly patients with colorectal carcinoma. Langenbecks Arch Surg. 2014;399:77–84.

139. Ho B, Lewis A, Paz IB. Laparoscopy can safely be performed in frail patients undergoing colon resection for cancer. Am Surg. 2017;83:1179–1183.

140. Otsuka K, Kimura T, Hakozaki M, et al. Comparative benefits of laparoscopic surgery for colorectal cancer in octogenarians: a case-matched comparison of short- and long-term outcomes with middle-aged patients. Surg Today. 2017;47:587–594.

141. Kazama K, Aoyama T, Hayashi T, et al. Evaluation of short-term outcomes of laparoscopic-assisted surgery for colorectal cancer in elderly patients aged over 75 years old: a multi-institutional study (YSURG1401). BMC Surg. 2017;17:29.

142. Devoto L, Celentano V, Cohen R, Khan J, Chand M. Colorectal cancer surgery in the very elderly patient: a systematic review of laparoscopic versus open colorectal resection. Int J Colorectal Dis. 2017;32:1237–1242.

143. Lo BD, Leeds IL, Sundel MH, et al. Frailer patients undergoing robotic colectomies for colon cancer experience increased complication rates compared with open or laparoscopic approaches. Dis Colon Rectum. 2020;63:588–597.

144. Li Y, Wang S, Gao S, Yang C, Yang W, Guo S. Laparoscopic colorectal resection versus open colorectal resection in octogenarians: a systematic review and meta-analysis of safety and efficacy. Tech Coloproctol. 2016;20:153–162.

145. Seishima R, Okabayashi K, Hasegawa H, et al. Is laparoscopic colorectal surgery beneficial for elderly patients? A systematic review and meta-analysis. J Gastrointest Surg. 2015;19:756–765.

146. Frasson M, Braga M, Vignali A, Zuliani W, Di Carlo V. Benefits of laparoscopic colorectal resection are more pronounced in elderly patients. Dis Colon Rectum. 2008;51:296–300.

147. Hatakeyama T, Nakanishi M, Murayama Y, et al. Laparoscopic resection for colorectal cancer improves short-term outcomes in very elderly colorectal cancer patients. Surg Laparosc Endosc Percutan Tech. 2013;23:532–535.

148. Hemandas AK, Abdelrahman T, Flashman KG, et al. Laparoscopic colorectal surgery produces better outcomes for high risk cancer patients compared to open surgery. Ann Surg. 2010;252:84–89.

149. Kozman MA, Kozman D. Laparoscopic colorectal surgery is safe and may be beneficial in patients eighty years of age and over. Open J Gastroenterol. 2012;2:76–80.

150. Lian L, Kalady M, Geisler D, Kiran RP. Laparoscopic colectomy is safe and leads to a significantly shorter hospital stay for octogenarians. Surg Endosc. 2010;24:2039–2043.

151. Nakamura T, Sato T, Miura H, et al. Feasibility and outcomes of surgical therapy in very elderly patients with colorectal cancer. Surg Laparosc Endosc Percutan Tech. 2014;24:85–88.

152. Gill TM, Allore HG, Gahbauer EA, Murphy TE. Change in disability after hospitalization or restricted activity in older persons. JAMA. 2010;304:1919–1928.

153. Lamont CT, Sampson S, Matthias R, Kane R. The outcome of hospitalization for acute illness in the elderly. J Am Geriatr Soc. 1983;31:282–288.

154. Banks E, Byles JE, Gibson RE, et al. Is psychological distress in people living with cancer related to the fact of diagnosis, current treatment or level of disability? Findings from a large Australian study. Med J Aust. 2010;193:S62–S67.

155. IPSOS MORI. Exploring the attitudes and behaviours of older people living with cancer. August 25, 2015. Available at https://www.ipsos.com/ipsos-mori/en-uk/exploring-attitudes-and-behaviours-older-people-living-cancer

156. Montroni I, Ugolini G, Saur NM, et al. Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer. Eur J Surg Oncol. 2018;44:1685–1702.

157. Pędziwiatr M, Pisarska M, Major P, et al. Laparoscopic colorectal cancer surgery combined with enhanced recovery after surgery protocol (ERAS) reduces the negative impact of sarcopenia on short-term outcomes. Eur J Surg Oncol. 2016;42:779–787.

158. Calle A, Onder G, Morandi A, et al. Frailty related factors as predictors of functional recovery in geriatric rehabilitation: the sarcopenia and function in aging rehabilitation (SAFARI) multi-centric study. J Nutr Health Aging. 2018;22:1099–1106.

159. Katz S, Akpom CA. A measure of primary sociobiological functions. Int J Health Serv. 1976;6:493–508.

160. Ketelaars L, Pottel L, Lycke M, et al. Use of the Freund clock drawing test within the Mini-Cog as a screening tool for cognitive impairment in elderly patients with or without cancer. J Geriatr Oncol. 2013;4:174–182.

161. De Roo AC, Li Y, Abrahamse PH, Regenbogen SE, Suwanabol PA. Long-term functional decline after high-risk elective colorectal surgery in older adults. Dis Colon Rectum. 2020;63:75–83.

162. Kuryba AJ SN, Hill J, van der Meulen JH, Walker K. Determinants of stoma reversal in rectal cancer patients who had an anterior resection between 2009 and 2012 in the English National Health Service. . Colorectal Dis;18:199-205.

163. Shahrokni A, Alexander K. What will perioperative geriatric assessment for older cancer patients look like in 2025? Advantages and limitations of new technologies in geriatric assessment. Eur J Surg Oncol. 2020;46:305–309.

164. Gensheimer SG, Wu AW, Snyder CF; PRO-EHR Users’ Guide Steering Group; PRO-EHR Users’ Guide Working Group. Oh, the places we’ll go: patient-reported outcomes and electronic health records. Patient. 2018;11:591–598.

165. Zerillo JA, Schouwenburg MG, van Bommel ACM, et al; Colorectal Cancer Working Group of the International Consortium for Health Outcomes Measurement (ICHOM). An international collaborative standardizing a comprehensive patient-centered outcomes measurement set for colorectal cancer. JAMA Oncol. 2017;3:686–694.

166. Hughes ME, Waite LJ, Hawkley LC, Cacioppo JT. A short scale for measuring loneliness in large surveys: results from two population-based studies. Res Aging. 2004;26:655–672.

167. Basch E, Deal AM, Dueck AC, et al. Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment. JAMA. 2017;318:197–198.