实验室检测指标（抗体类型和滴度、补体活性）与 MG 的关系是怎样的？

参考文献

[1] Ullah U, Iftikhar S, Javed MA. Relationship between Low and High Anti-acetylcholine Receptor Antibody Titers and Clinical Severity in Myasthenia Gravis. J Coll Physicians Surg Pak. 2021 Aug;31(8):965-968. 

[2] Somnier FE. Clinical implementation of anti-acetylcholine receptor antibodies. J Neurol Neurosurg Psychiatry. 1993 May;56(5):496-504. 

[3] Heldal AT, Eide GE, Romi F, Owe JF, Gilhus NE. Repeated acetylcholine receptor antibody-concentrations and association to clinical myasthenia gravis development. PLoS One. 2014 Dec 2;9(12):e114060. 

[4] Sanders DB, Burns TM, Cutter GR, Massey JM, Juel VC, Hobson-Webb L; Muscle Study Group. Does change in acetylcholine receptor antibody level correlate with clinical change in myasthenia gravis? Muscle Nerve. 2014 Apr;49(4):483-6. 

[5] Bartoccioni E, Scuderi F, Minicuci GM, Marino M, Ciaraffa F, Evoli A. Anti-MuSK antibodies: correlation with myasthenia gravis severity. Neurology. 2006 Aug 8;67(3):505-7. 

[6] Mori T, Sato A, Oka A, Higuchi O, Mizuguchi M. Anti-lipoprotein receptor-related protein 4 antibody titer correlates with the clinical course of myasthenia gravis. Pediatr Int. 2022 Jan;64(1):e14916. 

[7] Inoue H, Yamada K, Fujii A, Tomonari T, Mizuno K, Mita K, Higuchi O, Akao M, Matsukawa N. A Patient with Fulminant Myasthenia Gravis Is Seropositive for Both AChR and LRP4 Antibodies, Complicated by Autoimmune Polyglandular Syndrome Type 3. Intern Med. 2020 Sep 1;59(17):2177-2181.

[8] Fichtner ML, Hoarty MD, Vadysirisack DD, Munro-Sheldon B, Nowak RJ, O'Connor KC. Myasthenia gravis complement activity is independent of autoantibody titer and disease severity. PLoS One. 2022 Mar 15;17(3):e0264489.