理解的对吗?
A diverse array of proteins and other mediators have been identified on the surfaces of urate crystals. In addition to their proinflammatory effect through opsonizing existing crystals, immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies may promote crystal formation by providing a stable molecular platform for crystal nucleation and growth. Apolipoproteins are the best characterized of the antiinflammatory molecules that coat crystals. The characteristics of the phagocytes encountering the crystals may be crucial; macrophages that are more differentiated are less likely to elicit proinflammatory cytokines.
在尿酸盐晶体表面发现了一系列不同的蛋白质和其他受体。免疫球蛋白M(IgM)和免疫球蛋白G(IgG)抗体除了通过调理现有晶体发挥促炎作用外,还可以通过为晶体形核和生长提供稳定的分子平台来促进晶体的形成。载脂蛋白是一种抗炎分子,其最明显的特征是包裹晶体。与晶体接触的吞噬细胞的特征可能是至关重要的;分化程度较高的巨噬细胞不太可能激发促炎细胞因子。
Apolipoproteins are the best characterized of the antiinflammatory molecules that coat crystals.
载脂蛋白是一种抗炎分子,其最明显的特征是包裹晶体?
mediators 受体
crystal nucleation晶体形核
理解的对吗?谢谢
最后编辑于 2020-11-14 · 浏览 903