求翻译safety end points是什么东东,和primary end points有什么关联啊
Safety end points included severe or life-threatening bleeding and moderate bleeding during the hospital stay, as assessed according to the Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) criteria15; peripheral ischemic vascular complications requiring surgical or inter-ventional therapy; sepsis with clinical signs of in-fection and elevated procalcitonin levels (2 ng per milliliter or higher); and stroke, identified by the presence of new neurologic symptoms in conjunction with signs of ischemia or bleeding on computed tomography.