请问subconfluent 及confluent cells什么区别
In our human primary schwannoma model, no change in N-cadherin expression was observed at the protein level in subconfluent schwannoma cells . However, in accordance with data in different tumors including meningioma, a decrease in N-cadherin combined with strongly increased phosphorylation of β-catenin at Y654 was detected in confluent schwannoma cells, compared with Schwann cells。
文献为标题“Merlin-deficient human tumors show loss of contact inhibition and activation of Wntβ-catenin signaling linked to the PDGFRSrc and RacPAK pathways.”
上段话 大致是讲在subconfluent schwannoma cells及subconfluent schwannoma cells 观察到不同的现象,以前也有在文献中类似碰到 亚融合状态和融合状态的细胞 ,似乎是不一样的,大致觉得应该是融合的程度不一样。 请大侠具体的讲下他们的区别,还是融合是怎么样的,是2个细胞紧贴在一起,还是它们变成了一个细胞?
最后编辑于 2012-04-20 · 浏览 9373