单侧肾动脉狭窄（Unilateral renal artery stenosis ）会怎样

Unilateral renal artery stenosis causes hypoperfusion and activation of the renin-angiotensin-aldosterone system.  Angiotensin II causes arteriolar vasoconstriction and increases aldosterone and antidiuretic hormone synthesis.  The resultant hypertension helps reduce the decline in glomerular filtration rate in the affected kidney, but causes a pressure natriuresis with increased sodium excretion in the unaffected kidney.

 单侧肾动脉狭窄导致肾素-血管紧张素-醛固酮系统的灌注不足和激活。血管紧张素II引起小动脉血管收缩，并增加醛固酮和抗利尿激素的合成。由此产生的高血压有助于减少患侧肾脏中肾小球滤过率的下降，但会导致压力性利尿，并在健侧肾脏中增加钠排泄。