外泌体表征之电镜表征

备注：这里同时包括细胞外膜囊泡（EVs）和外泌体。

1PMID: 34385682，Nature Nanotechnology，IF：38.3。

Representative TEM image of purified exosomes from WM9 cells. Scale bar, 50 nm.

2PMID: 35273100，Journal for Immunotherapy of Cancer，IF：10.9。

Exosomes morphology detected by scanning electron microscope.

3PMID: 33133428，Journal of Extracellular Vesicles，IF：17.337。

TEM images of purified exosomes from WT, Pd-l1−/-, WT+IFN-γ, Pd-l1−/-+IFN-γ and WT+PD-L1. Scale bar: 50 nm.

4PMID: 35967739，Materials Today. Bio，IF：10.761。

TEM image of ADSC secreted exosome.

5PMID: 29290800，Theranostics，IF：11.6。

Morphology of UCB-Exos observed by TEM. Scale bar: 50 nm.

6PMID: 30662554，Theranostics，IF：11.6。

TEM micrograph of AMSCs-exo, scale bar: 200 nm.

7PMID: 38653959，Nature Communications，IF：16.6。

TEM images of (i) exosomes; (ii) ONB; (iii) EBO. Scale bar: 50 nm.

8PMID: 37342075，Advanced Materials (Deerfield Beach, Fla.)，IF：29.4。

ADSC-exos morphology analysis using electron microscopy; scale bar: 100 nm.

9PMID: 34020670，Journal of Nanobiotechnology，IF：10.2。

The morphology of the exosomes and PGZ-Exos was visualized with TEM. Scale bar: 50 nm.

10PMID: 35164758，Molecular Cancer，IF：41.444。

Visualization of purified FHC/HCT116/DLD1-Exos. TEM was performed to confirm the shape of the exosomes. Scale bar, 100 nm.

11PMID: 35386342，Bioactive Materials，IF：16.874。

SEM images of exosomes and Dox@Exos, respectively.

12PMID: 33172926，Gut，IF：31.793。

TEM images of purified Ex and Fn-Ex. Scale bar=100 nm.

13PMID: 32128074，Journal of Extracellular Vesicles，17.337。

Representative results of the nano-size vesicles photographed by transmission electron microscope. Scale bar, 100 nm.

14PMID: 37753374，Materials Today. Bio，IF：10.761。

The morphology of PHI-HA-mEXO after cryogenic storage for one month.

15年代久远的文献2010年，PMID: 19966785，Nature Cell Biology，IF：28.213。

Exosomes purified from cell culture supernatants were negatively stained and analysed by electron microscopy . Scale bar, 200 nm.

16PMID: 31258881，Journal of Extracellular Vesicles，IF：17.337。

Transmissionelectron microscopic view of isolated exosomes (e, average size 63 ± 15 nm, Mean ±SD; 78% vesicles in the range of 50–150 nm).

17PMID: 38225729，Advanced Science (Weinheim, Baden-Wurttemberg, Germany)，IF：15.1。

Transmission electron microscopy images showing the characteristic morphology of exosomes.

18PMID: 38158074，American Journal of Obstetrics and Gynecology，IF：10.693。

Representative transmission electron micrographs depicting the morphology of large EVs with an approximate diameter of 200 nm (yellow arrow), and (C) small EVs with diameters of approximately 60 nm (yellow arrow).

19PMID: 38179654，Journal of Extracellular Vesicles，IF：17.337。

Schematic overview of sEV purification process including a TEM image of bulk sEVs.

Schematic overview of the size-based separation of sEV subpopulations using SEC, alongside an UV chromatogram of the SEC run and TEM pictures of subpopulations defined as P1, P2 and P3.

20PMID: 34033477，ACS applied materials & interfaces，IF：10.383。

EM images of blank exosomes and FA-ExoICG. Scale bars are 50 nm.