Curcumin can improve Parkinson’s disease via activating BDNF/PI3k/Akt signalin
Parkinson’s disease is a common progressive neurodegenerative disease, and presently has no curative agent.
Curcumin, as one of the natural polyphenols, has great potential in neurodegenerative diseases and other
different pathological settings. The brain-derived neurotrophic factor (BDNF) and phosphatidylinositol 3 kinase
(PI3k)/protein kinase B (Akt) signaling pathways are significantly involved nerve regeneration and anti-
apoptotic activities
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