找全职博后， PhD and/or MD均可，有意者速度联系

Type: Full-Time

Posted: 07/25/2023

Postdoctoral Fellow, Department of Integrative Biology and Pharmacology – McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth Houston)

Location: Houston, TX

Open Date: Sep 1, 2023

Deadline:

Description

Dr. Xiaoqin Wu's lab in the Department of Integrative Biology and Pharmacology at UTHealth Houston is seeking highly motivated postdoc fellows who are interested in metabolic research.

The long-term research goal of my lab is to 1) understand the molecular mechanisms for regulating intracellular and extracellular vesicle trafficking and cell death in both metabolic homeostasis and disease; 2) identify novel therapeutic targets and biomarkers for obesity and fatty liver diseases; 3) repurpose existing drugs for metabolic disease. Given the strong association of Mixed Lineage Kinase Domain Like Pseudokinase (MLKL) with the regulation of cell death (canonical) and vesicle trafficking (non-canonical), the current focus is specifically on exploring the cell-specific, canonical and non-canonical roles of MLKL in physiological and pathophysiological conditions.

The lab uses genetically engineered mice and a broad spectrum of techniques such as confocal imaging, intravital imaging, RNA-sequencing, and proteomics techniques and bioinformatics approaches paired with targeted mechanistic strategies to explore the basis and functional consequences of dysregulated homeostatic signaling from both patients and mouse models.

Qualifications:

Candidates should have a PhD and/or MD degree with a solid background in molecular biology and cell biology. Previous experience in cellular imaging and experimental hepatology is preferable.

Contact:

Interested individuals should send their curriculum vitae and contact information of three references and brief descriptions of their current research and future objectives to Xiaoqin.Wu@uth.tmc.edu.