微量元素诱导桥本甲状腺炎发生发展的研究进展(述评)
李佩花△, 王丽, 赵乃倩
作者单位:030001 太原,山西医科大学第二临床医学院(李佩花);030001 太原,山西医科大学第二医院(王丽,赵乃倩)
摘要:
桥本甲状腺炎(HT)是在遗传易感性的基础上,由环境因素触发的一种自身免疫性疾病。微量元素是环境因素的重要组成部分,其中碘过量、硒缺乏、镁缺乏和维生素D缺乏是诱导HT发生发展的危险因素。这些微量元素诱导HT发生发展的机制与甲状腺自身免疫反应、氧化应激反应和炎症反应的激活有关。对于HT易感人群及HT患者,要给予合理的饮食指导,从而延缓HT的发生发展。
Abstract:
Hashimoto's thyroiditis (HT) is an autoimmune disease triggered by environmental factors on the basis of genetic susceptibility. Trace elements are an important part of environmental factors, among which iodine excess, selenium deficiency, magnesium deficiency and vitamin D deficiency are the risk factors inducing the incidence and progression of HT. The mechanism of HT induced by these nutritional factors is related to the activation of thyroid autoimmune response, oxidative stress response and inflammatory response. For HT susceptible population and HT patients, rational dietary guidance should be given, and corresponding nutritional supplements should be delivered when necessary, aiming to delay the incidence and progression of HT.
Key words: Hashimoto's thyroiditis, Iodine, Selenium, Magnesium, Vitamin D
链接本文: https://www.xinyixue.cn/CN/10.3969/j.issn.0253-9802.2023.05.001
最后编辑于 2023-06-13 · 浏览 947