理解的对吗？头大了

It’s important to recognize we are in the very early stages of understanding the potential clinical significance of P-SILI. The extent of lung injury induced by negative pleural pressure swings when the resulting global strain is limited to 5-8 mL/kg vs. 12-15 mL/kg is likely substantial and clinically relevant in terms of balancing risk factors affecting outcomes. These issues must be better understood before altering sedation practices as “prophylaxis” against PSILI (see below).

ARDS患者自戕性肺损伤（P-SILI）

重要的是要认识到，我们对P-SILI潜在临床意义的理解还非常肤浅。当全肺应力限制在导致潮气量5-8毫升/公斤或12-15毫升/公斤时时，就权衡影响预后的风险因素而言，胸腔负压的大小对肺损伤影响相当大，与临床上息息相关。这些问题在将镇静措施作为对P-SILI的“预防”之前，必须得到更好地理解(见下文)。

理解的对吗？头大了