先有严重的器官受累才能有口腔溃疡吗？？

1.  The buccal aphthosis of Behçet’s disease is recurrent (> three attacks per year) and must be objectified by a physician. It does not systematically precede severe organ involvement (ocular, neurological, and/or cardiovascular) but physicians must systematically ask about it.

白塞氏病的颊部口疮是复发性的（每年发作 3 次以上），必须由医生确认。它不会系统地发生在严重的器官受累（眼部、神经系统和/或心血管系统）之前，但医生必须系统地询问它。

问题：先有严重的器官受累才能有口腔溃疡吗？？

补充：我刚才又看到一个句子“Aphthous oral ulcers are usually the first and most persistent

clinical feature of BD.” 这句话是说溃疡先出现