activity、CNS是什么？

When patients with rheumatoid disorders present with neuropsychiatric symptoms, lumbar puncture can provide a useful diagnostic screening. First, it can serve to rule out the presence of a central nervous system (CNS) infection. Second, it provides an indication of overall disease activity in the CNS. In the absence of a CNS infection, increased CNS protein levels and/or CNS pleocytosis suggest CNS activity of the rheumatoid disorder (5). Another CNS marker useful in such cases is the presence of oligoclonal bands in the cerebrospinal fluid (CSF). This suggests an increased probability of acute CNS involvement in lupus or Sjögren syndrome, although it can also occur in cases of multiple sclerosis or Lyme disease (6).

当风湿疾病患者出现神经精神症状时，腰椎穿刺术可以提供有用的诊断筛查。首先，它可以用来排除中枢神经系统（CNS）感染的存在，其次它提供了中枢神经系统疾病总体受风湿疾病影响的指标。在没有中枢神经系统感染的情况下，脑脊液蛋白水平升高和/或脑脊液细胞增多提示风湿疾病的中枢神经系统受累（5）。在这种情况下，另一个提示风湿疾病时中枢神经系统受累的中枢神经系统标志物是脑脊液（CSF）中存在寡克隆条带。这表明急性中枢神经系统受累于狼疮或Sjögren综合征的可能性增加，尽管多发性硬化症或莱姆病也可能发生这种情况（6）。

这里红色的 activity受影响，受累？CNS脑脊液？

对吗？谢谢