THSD7A怎么理解？

Membranous nephropathy may be primary or secondary. Primary membranous nephropathy is due to in situ deposition of antibodies directed against a glomerular antigen. In 70% or more cases, the epitope is identified as phospholipase A2 receptor. A second, less-common epitope is thrombospondin type-1 domain-containing 7A (THSD7A). Proteinuria in membranous nephropathy may be massive. Secondary membranous nephropathy is often due to infection (e.g., hepatitis B, malaria, schistosomiasis, syphilis), autoimmune disease (e.g., systemic lupus erythematosus [SLE]), medications (e.g., D-penicillamine, gold), and malignancies. Distinguishing between the two subtypes is important for management (see following text).

l 膜性肾病：可能是原发性的，也可能是继发性的。原发性膜性肾病是由于针对肾小球抗原的抗体在原位沉积所致。70%以上的抗原决定部位被确定为磷脂酶A2受体，其次（不太常见）是含7A的血小板反应蛋白1型结构域 (thrombospondin type-1 domain-containing 7A，THSD7A)。膜性肾病的蛋白尿可能很严重。继发性膜性肾病通常是由感染(如乙型肝炎、疟疾、血吸虫病、梅毒)、自身免疫性疾病(如系统性红斑狼疮)、药物(如右旋青霉胺、金制剂)和恶性肿瘤引起的。区分这两种亚型对治疗很重要(见下文)。

THSD7A怎么理解？谢谢