理解的对吗?
EVALUATION OF POLYURIA
In patients with polyuria, the urine metabolic panel gives more information than the measured urine osmolality. The urine creatinine concentration or the urine to plasma creatinine ratio in a spot urine sample can identify patients with a large urine output (>3 L/day or 125 mL/h). Urine output (V) can be divided conceptually into two portions—osmolar clearance (Cosm) and **** water clearance (CH2O):
V(mL/h)=Cosm(mL/h)+CH2O(mL/h)
Osmolar clearance is simply the rate of solute excretion (UosmV) divided by plasma osmolality [10]. Except for extremely rare cases of pseudohyponatremia, estimated plasma osmolality (ePosm), calculated from values in the basic metabolic blood panel (Table 1), can substitute for plasma osmolality measured by osmometer. To distinguish between an osmotic and water diuresis, all that is needed is a spot urine sample, a concurrent plasma sample and an autoanalyzer
多尿症的评价
在多尿症患者中,尿液代谢组套检查比尿渗透压的测量能提供更多的信息。随机尿标本中的尿液肌酐浓度或尿液与血浆肌酐比值可以识别出高尿量的患者(>3 L/day或125 mL/h)。尿量(V)在概念上可分为两个部分——渗透清除(Cosm)和游 离 水清除(CH2O):
V(mL/h)=Cosm(mL/h)+CH2O(mL/h)
渗透清除就是溶质排泄率(UosmV)除以血浆渗透压。除了极罕见的假性低钠血症,根据基本代谢血液组套(表1)的方法估算的血浆渗透压(ePosm)可以代替渗透仪测量的血浆渗透压。为了区分渗透性利尿和水利尿,所需要的只是一个随机尿标本以及同时的血浆样本和一个自动分析仪(表1)。
理解的对吗?谢谢
最后编辑于 2022-10-09 · 浏览 2464