一个指数与死亡或心肌梗死独立相关?
Assessment of Functional Capacity and Stress Testing for Myocardial Ischemia
Poor functional capacity is associated with increased risk of perioperative complications.Patients unable to perform workloads of 4 METs or greater, such as walking up a hill or climbing 2 or more flights of stairs, have a 2-fold increased risk of perioperative cardiovascular complications compared with those who are able (9.6% vs 5.2%, respectively;P = .04).Among 1396 patients, the quantitative Duke Activity Status Index, derived from a validated questionnaire assessing functional capacity (range, 0-58.2; higher values indicate greater functionality),was independently associated with death or myocardial infarction in 28 patients (2%) within 30 days of surgery (adjusted OR, 0.91 [95% CI, 0.83-0.99]) for every 3.5 points on the index; however, theabsolute event rates corresponding to the ORs were not available).
心肌缺血的功能容量(functional capacity)和负荷试验评价
功能容量差与围术期并发症的风险增加相关。不能完成≥4MET(如步行上山或爬2级或更多楼梯)工作负荷的患者,围术期心血管并发症的风险是能完成患者的2倍(分别为9.6%和5.2%;P=0.04)。在1396名患者中,量化的杜克活动状况指数(来自有效的评估功能能力的问卷,数值范围0-58.2;更高的值表明功能状态更强)与28名患者(占2%)手术后30天内死亡或心肌梗死独立相关(杜克活动指数每降低3.5对应调整后OR为0.91[95%CI,0.83-0.99]);然而,缺乏与OR对应的绝对事件发生率数据)。
一个指数与死亡或心肌梗死独立相关?总觉得怪怪的,指数高或低 与 死亡或心肌梗死独立相关 是可以理解的,但本身指数应该说明不了问题。
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