non-syndromic啥意思？

What is the risk of coexisting congenital anomalies? 

Approximately 40% of patients with a CDH have coexisting congenital anomalies that can occur as part of a known syndrome or as an isolated finding. Cardiovascular malformations occur in approximately 10–15% of non-syndromic cases, while central nervous system anomalies including neural tube defects and hydrocephalus occur in 5–10% of non-syndromic cases. Limb anomalies occur in approximately 10% of non-syndromic cases of CDH

共存的先天畸形的风险有多大？

大约40%的CDH患者同时存在先天畸形，这些先天畸形可能是已知综合征的一部分，也可能是孤立的发现。心血管畸形发生在大约10%-15%的非综合征病例中，而中枢神经系统异常(包括神经管缺陷和脑积水)发生在5%-10%的非综合征病例中。肢体异常出现在大约10%的非综合征型的CDH病例中

non-syndromic啥意思？就是上面说的isolated孤立的？