到底是可以用还是不可以用？

In 2004, the FDA issued a “black box warning” For promethazine regarding its use in children under the age of 2 years, and an increased warning for use in children older than the age of two [25]. Promethazine is associated with adverse events including fatal respiratory depression and it should not be used in children under the age of two. There should be a very strong reason for use in children over 2 years of age,especially when given with other respiratory depressants such as opiates or anesthetics. If it is given in a child post-operatively, apnea monitoring should be strongly considered,at least in the form of continuous pulse oximetry.

2004年，FDA发布了关于异丙嗪在2岁以下儿童使用的“黑匣子警告”，并增加了对2岁以上儿童使用的警告[25]。异丙嗪与包括致命呼吸抑制在内的不良事件有关，不应用于两岁以下的儿童。对于2岁以上的儿童应该有非常充分的理由使用，特别是在与其他呼吸抑制剂(如鸦片类药物或麻醉剂)一起使用时。如果是在儿童手术后给予，则应积极考虑进行呼吸暂停监测，至少以连续脉搏血氧饱和度的形式进行监测。

 a very strong reason for use 对使用 有非常充分的理由 到底是可以用还是不可以用？从意思上应该是不可以用，从语法上怎么解释？