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Almost all commonly used anesthetics are teratogenic in some animal species. Anesthetic agents cause reversible decreases in cell motility, prolongation of DNA synthesis,and inhibition of cell division in mammalian cells experiments [3].

However, in order to induce a defect formation, a teratogenic drug must be given in an appropriate dosage, during a particular developmental stage of the embryo, in a species or individual with a particular genetic susceptibility[3]. Most scientists agreed that any drug can be teratogenic in an animal if enough is given at the right time. A small dose of a teratogen may cause structural abnormality or death in the susceptible early embryo, whereas much larger doses may demonstrate benign to the fetus.

在某些动物物种中，几乎所有常用的麻醉药都是致畸的。麻醉剂在哺乳动物细胞实验中引起可逆性的细胞活力降低、DNA合成延长和细胞分裂抑制[3]。

然而，为了诱导缺陷的形成，在胚胎的特定发育阶段，在具有特定遗传易感性的物种或个体中，必须给予适当剂量的致畸药物[3]。大多数科学家一致认为，如果在正确的时间给予足够的药物，任何药物都可能对动物产生致畸作用。小剂量的致畸剂可能会导致易感早期胚胎的结构异常或死亡，而大剂量的致畸剂可能对胎儿是良性的。

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