是如何分组的?
The second trial evaluated CYC (intravenously at a dose of 600 mg/m2/month) compared with placebo in 45 patients with SSc-ILD.59 Active treatment included six infusions of CYC given at 4-week intervals followed by oral azathioprine (2.5 mg/kg/day) or placebo for 6 months. Prednisolone (20 mg on alternate days) was co-administered in the active treatment group. The mean adjusted between-group difference in FVC was 4.2% in favour of CYC, which just missed statistical significance (p=0.08). The lung diffusing capacity for carbon monoxide and other outcome measures did not improve.59
第二项试验在45例SSc-ILD患者中对CYC(静脉注射剂量为600 mg / m2 /月)和安慰剂进行了评估.59 积极治疗包括输注CYC6次,每隔4周一次,口服硫唑嘌呤(2.5 mg/kg/天)或安慰剂,疗程6个月。积极治疗组同时服用强的松(每隔一天服用20毫克)。FVC组间差异的平均校正值为4.2%,有利于CYC,差一点达到统计学意义(p=0.08)。一氧化碳的肺部扩散能力和其他结果指标没有改善。59
是如何分组的?
1治疗组:CYC(静脉注射剂量为600 mg / m2 /月)+强的松 继而硫唑嘌呤
安慰剂组
2、 硫唑嘌呤
治疗组:CYC(静脉注射剂量为600 mg / m2 /月)+强的松 继而分为上下两组
安慰剂
最后编辑于 2022-10-09 · 浏览 537