抗体工程 Antibody Engineering

编者： Roland Kontermann； Stefan Dübel

second edition

Part I  Bioinformatics of  Antigen-binding Sites

1 Analysis of Single Chain Antibody Sequences Using

2 Standardized Sequence and Strucuture Analysis

3 Protein Sequence and Structure Anlysis of Antibody

Part II  Generation of Antibody Fragments and Their Derivatives

4 scFv by Two-Step Cloning

5 Bivalent Diabodies

6 Generation of Single-Chain Fragments and Multivalent Derivatives scFv-Fc and scFv-CH3

7 Miniantibodies

8 Generation of Stably Transfected Eukaryotic Cell Lines Producing ImmunoRNAse Fusion Proteins

9 Antibody-Cytokine Fusion Proteins with Members of the TNF-Family

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Part III  Production of Antibody Fragments

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Part IV  Recombinant Antibody Molecules in Nanobiotechnology and Proteomics

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