【medical-news】【资讯翻译】 男性谢顶冠心病风险增加
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【资讯翻译】
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原文链接
：http://www.theheart.org/article/1525183.do
Male-pattern baldness linked with coronary heart disease
Vertex baldness, more commonly known as male-pattern baldness, is associated with an increased risk of coronary heart disease, according to the results of a new meta-analysis [1]. The severity of male pattern baldness increased the risk of coronary disease even in younger subjects, report investigators.
A receding hairline, on the other hand, was not associated with an increased risk of heart disease (relative risk 1.11, 95% CI 0.92-1.32; p=0.28).
"These findings suggest that vertex baldness is more closely associated with systemic atherosclerosis than . . . frontal baldness [is]," say Dr Kazuo Hara (University of Tokyo, Japan) and colleagues in their report, published online April 3, 2013 in BMJ Open. "Thus, cardiovascular risk factors should be reviewed carefully in men with vertex baldness, especially younger men, and they probably should be encouraged to improve their cardiovascular risk profile."
The researchers included six studies with 36 990 participants in the meta-analysis, including three cohort studies and three case-control studies. In the three cohort studies, the adjusted risk of coronary heart disease was 32% higher among individuals with severe vertex baldness compared with men with full hair. In the case-control studies, the risk of coronary heart disease was 70% higher among bald subjects compared with those without baldness. The increased relative risk of coronary disease was statistically significant in both analyses. When the analysis was restricted to younger subjects, those <55 or <60 years at baseline, the association between vertex baldness and coronary heart disease remained.
Three studies classified the severity of baldness. In this analysis, the risk of coronary heart disease was 48%, 36%, and 18% higher among subjects with severe, moderate, and mild vertex baldness compared with subjects without baldness. "When baldness was classified by the Hamilton-Norwood scale, which is the most commonly used classification of pattern baldness worldwide, the relationship between coronary heart disease and baldness was shown to be dependent on the severity of baldness," state the researchers.
The reason for the association between vertex baldness and coronary heart disease is not known. The current working hypothesis is that insulin resistance can impair the supply of nutrients to the hair follicles or a proinflammatory state could increase the inflammatory cytokines in the hair follicles. The researchers state that further studies are needed to confirm these findings, as well as to identify mechanisms for the association.
1.“认领本文翻译，若48小时内未完成，请其他战友认领！ ”
2.认领翻译的战友①请跟帖引用第一句话；②48小时完成翻译，贴出段对段翻译；③译文整理（并标明字数）；④根据战友回复修正译文。
3.请根据自己的专业背景选择相应的资讯认领，经常认领而不能及时提供优质稿件者将被列入黑名单，取消认领资格，请大家注意！
4.新近参与本次活动的会员请查看：【公告】动态版重启资讯翻译计划：我为人人，人人为我，共同提高
5.寻找最近的翻译贴请查看：点击进入
6.翻译时请参照版规 【版务】科技动态版版规及加分细则（ 2014-02-21 更新）
7.翻译三天未加分找 【版务】加分申诉点击
8.举报和合并加分专贴
【公告】版务管理之【举报和合并加分专贴】仅限于10分以下战友
9.希望参与动态版其他活动的会员请查看版面右边栏的置顶部分。
0.感谢您的阅读与参与！（翻译时请把不确定的地方用红色字体标注
）
原文链接
：http://www.theheart.org/article/1525183.do
Male-pattern baldness linked with coronary heart disease
Vertex baldness, more commonly known as male-pattern baldness, is associated with an increased risk of coronary heart disease, according to the results of a new meta-analysis [1]. The severity of male pattern baldness increased the risk of coronary disease even in younger subjects, report investigators.
A receding hairline, on the other hand, was not associated with an increased risk of heart disease (relative risk 1.11, 95% CI 0.92-1.32; p=0.28).
"These findings suggest that vertex baldness is more closely associated with systemic atherosclerosis than . . . frontal baldness [is]," say Dr Kazuo Hara (University of Tokyo, Japan) and colleagues in their report, published online April 3, 2013 in BMJ Open. "Thus, cardiovascular risk factors should be reviewed carefully in men with vertex baldness, especially younger men, and they probably should be encouraged to improve their cardiovascular risk profile."
The researchers included six studies with 36 990 participants in the meta-analysis, including three cohort studies and three case-control studies. In the three cohort studies, the adjusted risk of coronary heart disease was 32% higher among individuals with severe vertex baldness compared with men with full hair. In the case-control studies, the risk of coronary heart disease was 70% higher among bald subjects compared with those without baldness. The increased relative risk of coronary disease was statistically significant in both analyses. When the analysis was restricted to younger subjects, those <55 or <60 years at baseline, the association between vertex baldness and coronary heart disease remained.
Three studies classified the severity of baldness. In this analysis, the risk of coronary heart disease was 48%, 36%, and 18% higher among subjects with severe, moderate, and mild vertex baldness compared with subjects without baldness. "When baldness was classified by the Hamilton-Norwood scale, which is the most commonly used classification of pattern baldness worldwide, the relationship between coronary heart disease and baldness was shown to be dependent on the severity of baldness," state the researchers.
The reason for the association between vertex baldness and coronary heart disease is not known. The current working hypothesis is that insulin resistance can impair the supply of nutrients to the hair follicles or a proinflammatory state could increase the inflammatory cytokines in the hair follicles. The researchers state that further studies are needed to confirm these findings, as well as to identify mechanisms for the association.
