【drug-news】【资讯翻译】他汀类药物治疗引发慢性咳嗽
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http://www.medscape.com/viewarticle/768504?src=rss
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翻译时请参照版规 【版务】科技动态版版规及加分细则（ 2014-02-21 更新）
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Abstract
Statins are widely used for primary and secondary prevention of cardiovascular disease. For this reason, knowledge of the side effects and interactions pertaining to this class of pharmaceuticals is of utmost importance to all physicians. In this text a case report is presented of an eighty year old gentleman, referred to the respiratory clinic at Mater Dei Hospital Malta after developing dry cough on being treated with simvastatin and fluvastatin. An attempt at switching over to a placebo was made with resolution of symptoms. This is the second described case in the literature of lone cough associated with statin therapy necessitating treatment discontinuation in our patient. Possible hypothesis are discussed as well as suggestions for further research to unravel the underlying mechanisms of this association.
Introduction
Chronic persistent cough unresponsive to symptomatic treatment or persisting despite treatment of the underlying cause remains a common cause of referral for assessment by respiratory physicians. Chronic cough is said to be present when the duration of the cough exceeds 8 weeks and many causes have been implicated [Chung and Pavord, 2008]. Despite a thorough assessment, examination and use of relevant investigations, a cause may still not be identified thus constituting a diagnosis of idiopathic cough. However, the increased incidence of patients being positive to organ-specific autoantibodies suggests an association between idiopathic chronic cough and organ-specific autoimmunity
认领翻译的战友请跟帖注明“认领本文翻译，48小时内未完成，请其他战友认领！
请根据自己专业背景选择认领，如使用翻译软件翻译，被发现者扣分1-2分
请根据自己的专业背景选择相应的资讯认领，经常认领而不能及时提供优质稿件者将被列入黑名单，取消认领资格，请大家注意！
新近参与本次活动的会员请查看： http://news.dxy.cn/bbs/topic/21537141
寻找最近的翻译贴请查看： http://search.dxy.cn/?words=%E8%B5%84%E8%AE%AF%E7%BF%BB%E8%AF%91&bid=116&t=1&c=1&age=7&bid=116&limit=30&o=1
翻译时请参照版规 【版务】科技动态版版规及加分细则（ 2014-02-21 更新）
希望参与动态版其他活动的会员请查看版面右边栏的置顶部分。
Abstract
Statins are widely used for primary and secondary prevention of cardiovascular disease. For this reason, knowledge of the side effects and interactions pertaining to this class of pharmaceuticals is of utmost importance to all physicians. In this text a case report is presented of an eighty year old gentleman, referred to the respiratory clinic at Mater Dei Hospital Malta after developing dry cough on being treated with simvastatin and fluvastatin. An attempt at switching over to a placebo was made with resolution of symptoms. This is the second described case in the literature of lone cough associated with statin therapy necessitating treatment discontinuation in our patient. Possible hypothesis are discussed as well as suggestions for further research to unravel the underlying mechanisms of this association.
Introduction
Chronic persistent cough unresponsive to symptomatic treatment or persisting despite treatment of the underlying cause remains a common cause of referral for assessment by respiratory physicians. Chronic cough is said to be present when the duration of the cough exceeds 8 weeks and many causes have been implicated [Chung and Pavord, 2008]. Despite a thorough assessment, examination and use of relevant investigations, a cause may still not be identified thus constituting a diagnosis of idiopathic cough. However, the increased incidence of patients being positive to organ-specific autoantibodies suggests an association between idiopathic chronic cough and organ-specific autoimmunity
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