【摘要翻译】肾肿瘤自然病程的追踪观察
发布于 2003-12-26 · 浏览 1175 · IP 福建福建
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肾肿瘤自然病程的追踪观察(NATURAL HISTORY OF RENAL MASSES FOLLOWED EXPECTANTLY)
J Urol. 2004 Jan;171(1):111-3; discussion 113.
Kassouf W, Aprikian AG, Laplante M, Tanguay S.
McGill University Health Center, Montreal, Quebec, Canada.
ABSTRACT
Purpose: An increasing number of incidental renal masses have been detected with increasing use of ultrasonography, computerized tomography and magnetic resonance imaging. We investigated the natural history of incidentally detected renal masses.
Materials and Methods: A total of 24 patients were included in this retrospective analysis. Average patient age was 68.3 years (range 29 to 83). The 16 males and 8 females were followed with abdominal imaging for a mean and median followup of 31.6 and 24 months, respectively range 8 to 86). Patients elected to be observed because of age, poor medical condition or the presence of a mass in a solitary kidney. The majority of patients (22 of 24) were asymptomatic at diagnosis. Two patients were followed with bilateral renal masses, and 2 with T3b tumors. Of the 20 patients with incidental solitary renal masses, 6 were at the upper pole, 9 were mid polar and 5 lower pole. Mean maximum diameter of lesions was 3.3 cm (median 2.7, range 0.9 to 10). Growth rate was calculated based on diameter and tumor volume.
Results: Of the 24 patients only 5 demonstrated tumor growth during the surveillance period. No metastasis developed in any patients. Mean tumor growth rate observed in the 5 patients was 0.49 cm per year or 7.3 cc per year. Of the 24 patients 4 underwent surgery after surveillance because of apparent tumor growth or per patient request. Pathology revealed renal cell carcinoma in all 4.
Conclusions: Tumor growth of renal masses is often limited. Most of our patients did not demonstrate significant growth when followed expectantly. Without tumor growth the risk of metastasis seems limited.
中文摘要
目的：随着超声、CT、MRI应用的增多，肾偶发肿瘤也越来越多地被发现。本文我们探讨了肾偶发肿瘤地自然病程。
材料和方法：这次回顾性分析共包括24例患者，平均患者年龄为68.3岁（范围为29到83岁）。16例男性患者和8例女性患者采用腹部影像学检查平均随访时间分别为31.6个月和24个月（范围为8到86个月）。患者选择随访观察的原因是考虑到年龄、医疗条件差或肿瘤存在于孤立肾中。大多数患者（22/24）在诊断时是无症状的。随访的患者中两例为双侧肾肿瘤，两例为T3b期肿瘤。余下的20例患者为偶发孤立肾肿瘤，其中6例位于上极，9例位于中央，5例位于下极。肿瘤的平均最大直径为3.3cm（平均2.7，范围为0.9－10）。生长速度的计算是基于直径或肿瘤的体积。
结果：在观察期间，24例患者中仅有5例表现为肿瘤生长。在任何病例中均没有发生转移。观察的5例患者的肿瘤平均生长速度为0.49cm/年或7.3cc/年。24例患者中有4例观察期过后因为肿瘤生长或基于患者的要求采用了手术治疗。所有4例患者的病理检查均为肾细胞癌。
结论：肾肿瘤的生长常是有限的。大多数病人在追踪观察中并没有发现肿瘤显著的生长。肿瘤不生长，因而发生转移的危险性是低的。
J Urol. 2004 Jan;171(1):111-3; discussion 113.
Kassouf W, Aprikian AG, Laplante M, Tanguay S.
McGill University Health Center, Montreal, Quebec, Canada.
ABSTRACT
Purpose: An increasing number of incidental renal masses have been detected with increasing use of ultrasonography, computerized tomography and magnetic resonance imaging. We investigated the natural history of incidentally detected renal masses.
Materials and Methods: A total of 24 patients were included in this retrospective analysis. Average patient age was 68.3 years (range 29 to 83). The 16 males and 8 females were followed with abdominal imaging for a mean and median followup of 31.6 and 24 months, respectively range 8 to 86). Patients elected to be observed because of age, poor medical condition or the presence of a mass in a solitary kidney. The majority of patients (22 of 24) were asymptomatic at diagnosis. Two patients were followed with bilateral renal masses, and 2 with T3b tumors. Of the 20 patients with incidental solitary renal masses, 6 were at the upper pole, 9 were mid polar and 5 lower pole. Mean maximum diameter of lesions was 3.3 cm (median 2.7, range 0.9 to 10). Growth rate was calculated based on diameter and tumor volume.
Results: Of the 24 patients only 5 demonstrated tumor growth during the surveillance period. No metastasis developed in any patients. Mean tumor growth rate observed in the 5 patients was 0.49 cm per year or 7.3 cc per year. Of the 24 patients 4 underwent surgery after surveillance because of apparent tumor growth or per patient request. Pathology revealed renal cell carcinoma in all 4.
Conclusions: Tumor growth of renal masses is often limited. Most of our patients did not demonstrate significant growth when followed expectantly. Without tumor growth the risk of metastasis seems limited.
中文摘要
目的：随着超声、CT、MRI应用的增多，肾偶发肿瘤也越来越多地被发现。本文我们探讨了肾偶发肿瘤地自然病程。
材料和方法：这次回顾性分析共包括24例患者，平均患者年龄为68.3岁（范围为29到83岁）。16例男性患者和8例女性患者采用腹部影像学检查平均随访时间分别为31.6个月和24个月（范围为8到86个月）。患者选择随访观察的原因是考虑到年龄、医疗条件差或肿瘤存在于孤立肾中。大多数患者（22/24）在诊断时是无症状的。随访的患者中两例为双侧肾肿瘤，两例为T3b期肿瘤。余下的20例患者为偶发孤立肾肿瘤，其中6例位于上极，9例位于中央，5例位于下极。肿瘤的平均最大直径为3.3cm（平均2.7，范围为0.9－10）。生长速度的计算是基于直径或肿瘤的体积。
结果：在观察期间，24例患者中仅有5例表现为肿瘤生长。在任何病例中均没有发生转移。观察的5例患者的肿瘤平均生长速度为0.49cm/年或7.3cc/年。24例患者中有4例观察期过后因为肿瘤生长或基于患者的要求采用了手术治疗。所有4例患者的病理检查均为肾细胞癌。
结论：肾肿瘤的生长常是有限的。大多数病人在追踪观察中并没有发现肿瘤显著的生长。肿瘤不生长，因而发生转移的危险性是低的。
最后编辑于 2004-06-20 · 浏览 1175
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