HPV相关选择题

Which of the following statements is true regarding cervical oncogenesis and the genome of human papillomavirus (HPV)?关于宫颈癌发生与人乳头瘤病毒（HPV）基因组的关系，下列哪项陈述是正确的？ 

A. The E1 and E2 are most responsible for the cervical oncogenesis E1和E2蛋白是导致宫颈癌发生的主要因素

B. The E3 and E4 are the principal components of the HPV vaccines E3和E4蛋白是HPV疫苗的主要成分

C. L1 binds to the retinoblastoma tumor suppression protein pRB and abolishes cell-cycle arrest L1蛋白结合视网膜母细胞瘤肿瘤抑制蛋白pRB并解除细胞周期停滞

D. E6 binds to p53 and results in blocking of apoptosis E6蛋白结合p53并阻止细胞凋亡

E. E7 binds to p16 and results in proliferation of cells E7蛋白结合p16并促进细胞增殖

备注：以上编译来自胡佐鸿老师，仅供学习交流。