美国儿科学会：预防儿童食物过敏的最新进展

Updates in Food Allergy Prevention in Children 

Elissa M. Abrams, MD, MPH; Marcus Shaker, MD, MSc; David Stukus, MD; Douglas P. Mack, MD, MSc; Matthew Greenhawt, MD, MBA, MSc

Although significant evidence exists that feeding early has a role in the prevention of food allergy, this intervention in isolation may not be sufficient. Recent evidence highlights that early introduction of peanut specifically has had no significant impact on the populational prevalence of peanut allergy. Other factors that may contribute to food allergy prevention include regularity of ingestion once an allergen is introduced and consideration to the form in which the allergen is introduced (such as baked versus cooked egg). There are also many practicalities to early feeding and some discrepant viewpoints on these practicalities, which has led to poor implementation of early feeding strategies. In general, preemptive screening before food introduction is not recommended by most international allergy societies. Although there is little guidance to inform early introduction of allergens other than milk, egg, and peanut, the mechanism of sensitization is thought to be similar and there is no harm to early introduction. In terms of frequency and duration of feeding, there is little evidence to inform any concrete recommendations.

Subjects:Allergy/Immunology

Topics:allergens, food allergy, peanut hypersensitivity, peanuts, ingestion, hypersensitivity, food