“存在争议”与“已阐明”?
Acute lung injury (Chapter 31) is a serious complication that occurs in the postoperative period in between 2.5% and 9% of pneumonectomies, and more rarely follows smaller lung resections such as lobectomy.41 Mortality is high, with a quarter of patients dying. The pathophysiology of postpneumonectomy acute lung injury is controversial, with perioperative fluid overload viewed by many clinicians as the main cause, although the pathophysiology is now better elucidated and far more complex than simply administering excessive volumes of intravenous fluid. High-protein pulmonary oedema develops approximately 24 hours postoperatively, and is believed to result from endothelial cell injury in the pulmonary capillaries. How this initial injury occurs is less clear, although its origins almost certainly involve intraoperative OLV . Factors leading to potential damage of the ventilated lung during OLV include:
急性肺损伤(见第31章)是一种严重的并发症,全肺叶及全肺切除术后发生率2.5%~9%,小范围局部肺切除术(如肺叶切除术)后较少见41。一旦发生死亡率很高,四分之一的患者死亡。肺切除术后急性肺损伤的病理生理学存在争议,现有病理生理学已阐明其机制复杂,虽术后急性肺损伤的病因远非仅有静脉液体入量过负荷,但许多临床医生认为围术期液体过负荷是主要病因。由于肺毛细血管内皮细胞损伤,术后约24小时发生高蛋白渗出型肺水肿,肺毛细血管内皮细胞损伤的发生机制尚不清楚,但肯定与术中OLV有关。在OLV期间,导致通气肺潜在损伤的因素包括:
逻辑不通啊,前面说“肺切除术后急性肺损伤的病理生理学存在争议”后面说“现有病理生理学已阐明”,是否矛盾,
是不是是说better elucidated(已阐明)是“其机制是复杂的”,正因为“复杂的(more complex)”,所以它的机制是“controversial(存在争议)”的
最后编辑于 2022-10-09 · 浏览 8375