几组？P值？

FIGURE 1. Changes in noradrenaline requirements, blood pressure, renal medullary oxygenation and plasma creatinine in response to vitamin C (red squares, n=5) or vehicle (blue circles, n =5) treatment during ovine sepsis and recovery from Gram-negative infection. Noradrenaline dose mean arterial pressure, renal medullary oxygen tension (PO2) a n d p l a s m a creatinine during infusion of live Escherichia coli from 0 to 31 h of sepsis. All animals were initially resuscitated with fluid bolus therapy (Fluid BT, 30 ml/kg balanced crystalloid over 30 min) from 23.5 to 24 h of sepsis. Animals then randomized to receive sodium ascorbate (0.5 g/kg) or vehicle-crystalloid bolus therapy (VitC BT) from 24 to 24.5 h of sepsis followed by an infusion of sodium ascorbate (0.5 g/kg/h) or vehicle-crystalloid from 24.5 to 31 h of sepsis. Norepinephrine doses were titrated to maintain mean arterial pressure at baseline levels (75--80 mmHg) from 25 to 31 h of sepsis. Time 0 is the mean of the 24th hour of baseline, and times 23--31 h of sepsis are means of 0.5 h periods. The letter S before the hours indicates the time since the start of the study (S). Data are presented as treatment group-specific mean ? standard error. P values represent treatment--time interactions from a two-way repeated-measures analysis of variance from 23 to 31 h of Gram-negative sepsis.

图1.绵羊脓毒症和革兰氏阴性感染恢复期间维生素C（红色方块，n=5）或溶媒对照（蓝色圆圈，n=5）处理后的去甲肾上腺素需求、血压、肾髓质氧合和血浆肌酐变化。0-31 h输注活大肠埃希菌后脓毒症期间的去甲肾上腺素剂量、平均动脉压、肾髓质氧张力（PO₂）和血浆肌酐。所有动物最初均在脓毒症23.5至24 h期间通过液体推注治疗（30 mL/kg平衡晶体液，30 min）进行复苏。然后，在脓毒症24-24.5 h随机接受抗坏血酸钠 （VitC 0.5 g/kg，液体推注治疗） 或溶媒-晶体液推注治疗，随后在脓毒症24.5-31 h抗坏血酸钠组继续输注抗坏血酸钠（0.5 g/kg/h） 、溶媒-晶体液继续输注溶媒-晶体液。为将脓毒症25-31 h的平均动脉压维持在基线水平（75~80 mmHg），滴定去甲肾上腺素剂量。时间0是基线第24 h的平均值，时间23-31 h是脓毒症0.5 h期间的平均值。小时之前的字母S表示研究（study）开始后的时间（S）。数据表示为特定治疗组的均值±标准误。P值代表革兰氏阴性脓毒症23-31h双向重复方差分析的治疗-时间相互作用。

1.怎么从followed by后面看，后来又是2组，那不就应该是前面分2组，随后在两组基础上又是每组各分2组，那就应该是2乘以2=4组了？但是从这个图看，只有两组，难道是这个图只显示一直都是“维生素C组”和一直都是“溶媒对照”组的？

“维生素C组”一直是“维生素C组”，“溶媒对照”组一直是“溶媒对照”组？因为followed by后面没有randomized，而且一共每组才5个，估计没法再分组了

2.P值得说法也很怪，P值代表interactions？