这几个地方理解的对吗?
Anastomotic dehiscence following lung transplantation is characterized by necrosis leading to full-thickness anastomotic separation of the bronchial wall. Multiple grading systems have been proposed to describe airway complication following lung transplantation. Courad et al. published an early schema in 1992 based on bronchoscopic appearance of anastomosis on day 15 [6]. This system is graded.This system is graded as grade 1, complete primary mucosal healing; grade 2a, complete primary healing without necrosis, partial primary mucosal healing; grade 2b, complete primary healing without necrosis, no primary mucosal healing; grade 3a, limited focal necrosis (extending less than 5 mm from the anastomotic line); and grade 3b, extensive necrosis. However, this system does not address anastomotic stenosis, granulation tissue formation, or other potential findings with airway complications. Santacruz and Mehta have categorized airway complications following lung transplantation into six groups: stenosis, necrosis and dehiscence, exophytic granulation tissue, malacia, fistulae, and infections [7]. This system, however, does not differentiate anastomotic dehiscence from necrosis. The French Language Pulmonary Society (FLPS) has also proposed a system based on the macroscopic appearance, diameter, and suture (MDS) in 2013 [8]. The MDS system, however, lacks terminology for the severity of ischemia or necrosis. The International Society for Heart and Lung Transplantation (ISHLT) also offers a grade of dehiscence by location (cartilaginous, membranous, both) and extent (0–25%, >25–50%, >50% to 75%, >75% of circumference)
肺移植术后吻合口裂是以可导致支气管壁全层吻合口分离的坏死为特征。已提出多种分级系统来描述肺移植术后的气道并发症。Courad等研究者于1992年发表了一个基于第15天支气管镜下吻合术外观的早期分级示意图[6]。该系统进行如下分级:1级,粘膜完全一期愈合;2a级,完全一期愈合无坏死,部分粘膜一期愈合;2b级,完全一期愈合无坏死,无粘膜一期愈合;3a级,局限性灶性坏死(距吻合口<5mm);3b级,广泛坏死。然而,该系统并不包括吻合口狭窄、肉芽组织或其他潜在气道并发症。Santacruz和Mehta将肺移植后的气道并发症分为六组:狭窄、坏死和裂开、外生性肉芽组织、软化、瘘管和感染[7],但该系统并不能区分吻合口裂和坏死。法语肺科学会(French Language Pulmonary Society,FLPS)也于2013年提出了一种基于大体外观、直径和缝合(the macroscopic appearance, diameter, and suture,MDS)的系统[8]。然而,对缺血或坏死严重程度,MDS系统缺乏术语。国际心肺移植学会(the International Society for Heart and Lung Transplantation,ISHLT)也按部位(气管软骨、膜部以及两者)和程度(周长的0~25%、>25~50%、>50%~75%、>75%)的对裂开进行分级[9]。
这几个地方理解的对吗?
complete primary mucosal healing粘膜完全一期愈合
complete primary healing without necrosis, partial primary mucosal healing完全一期愈合无坏死,部分粘膜一期愈合
French Language Pulmonary Society 法语肺科学会
macroscopic appearance大体外观
cartilaginous气管软骨
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