世界首例心脏和胸腺联合移植的婴儿可能不要终生服用抗排异药物

Baby gets first heart and thymus transplant, possibly eliminating need for dangerous lifelong medication

When Kaitlyn Sinnamon was 20 weeks pregnant with her second child, doctors told her that her baby would be born with a heart defect that would require surgery at the beginning of his life.当Kaitlyn Sinnamon怀第二个孩子20周时，医生告诉她孩子有先天性心脏病，一出生就需要手术治疗

Easton Sinnamon was born at Duke University Hospital with single ventricle heart disease, which meant his heart had only one ventricle, instead of two, to pump blood to the rest of his body.

Easton Sinnamon在杜克大学医院出生，他患有单心室心脏病，这意味着他的心脏只有一个心室，而不是能把血液泵到身体其他组织两个心室。

After two heart surgeries couldn't correct a leaking heart valve related to his congenital heart disease, it became clear to his surgical team that Easton would need a new heart. But the transplant would require Easton to be on immune-suppressing medications for the rest of his life so his body wouldn't reject the new organ.

经历了两次心脏手术并没能纠正先天性心脏瓣膜漏，医生团队因此清楚Easton可能需要一个新的心脏。但是心脏移植，需要终身服用能够抑制器官排斥反应的免疫抑剂。

These medications can increase the risk of cancer and be toxic to the kidneys, as well as making patients more susceptible to severe infections.

这些药物会增加癌症风险及肾脏毒性，还会增加患严重感染性疾病的概率。

详见： https://edition.cnn.com/2022/03/10/health/baby-heart-and-thymus-transplant/index.html