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理解的对吗?

发布于 2021-12-23 · 浏览 778 · IP 江苏江苏
这个帖子发布于 3 年零 137 天前,其中的信息可能已发生改变或有所发展。

When analyses are limited to patients judged to have status myoclonus, cohort studies have consistently reported low false positive rates in the prediction of poor outcome (Fig. 1). Studies that have assessed the relationship between any myoclonus and poor outcomes have found a larger number of false positives. It is, however, unclear how consistently clinicians agree in their characterization of myoclonic jerks as meeting criteria for status myoclonus. It must also be acknowledged that verification bias, in which the presence of status myoclonus was a possible factor contributing to WLSM decisions, may have contributed to low false positive rates, especially in older literature. The only way to entirely avoid such bias is through studies in which early WLSM is uncommon.

当分析仅限于判定为肌阵挛状态的患者时,队列研究一致报告肌阵挛在预测不良结果方面假阳性率较低(图1)。然而评估肌阵挛与不良预后之间关系的研究则发现假阳性的数量更多。然而,目前尚不清楚临床医生在将肌阵挛性抽搐定性为肌阵挛状态的标准方面的一致性有多大。还必须承认,验证偏倚(其中肌阵挛状态可能是导致WLSM决定的一个因素)可能导致假阳性率较低(特别是在较古老的文献中)。完全避免这种偏倚的唯一方法是钻研早期WLSM不常见的研究。

最后编辑于 2022-10-09 · 浏览 778

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