求助这段话怎么翻译。

 Conceivably, in normal biology when basal stem cells undergo early differentiation through NOTCH1 activation, they detach from the basement membrane and would require additional or increased survival mechanisms. A similar process is likely to occur in HNSCC during the cascade of gene expression changes triggered by NOTCH1 signaling. The complex role of NOTCH1 activation in the tumorigenesis and phenotypic behavior of HNSCC would likely confound therapeutic strategies proposed to inhibit NOTCH1 signaling in this cancer type. Rather, the focus should be on elucidating and blocking pathways or survival mechanisms that might arise in subsets of HNSCC where NOTCH1 is activated.