【摘要翻译】【Eur J Orthod】女性特纳综合征患者及其父母颅面部显著特征的关系
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文题：The relationship of distinct craniofacial features between Turner syndrome females and their parents.
作者：Perkiomaki MR, Kyrkanides S, Niinimaa A, Alvesalo L.
杂志全名：European Journal of Orthodontics
年份，卷（期），起止页码：2005 Feb;27(1):48-52.
PMID：15743862
英文摘要：
SUMMARY The present study aimed to assess the relationship of craniofacial features between females with Turner syndrome (TS) and their parents. Lateral cephalograms of 63 TS females and 80 family members with normal karyotype were analysed using 13 linear and eight angular cephalometric measurements.The statistical differences of the measurements between adult TS females and their mothers (n = 41)and between adult TS females and their adult sisters (n = 27) were calculated to define the distinct craniofacial features of subjects with TS. Regression models were computed to assess the association of distinct craniofacial features between TS females and their parents (n = 41 for mothers and n = 12 forfathers).
Distinct craniofacial features of the subjects with TS were an increased cranial base flexion, shortened posterior cranial base length (S–Ba), retrognathic maxilla and mandible (<SNB ), shortened distance of the palate, glenoid fossa (S–Art) and gonion (S–Go) from sella, shortened body and total length (Art–Pog)of the mandible and increased vertical angles of the facial skeleton. The mothers’ S–Ba (P = 0.001),<SNB (P < 0.001), S–Go (P < 0.01) and S–Art (P < 0.05) measurements predicted well the corresponding measurements of their daughters with TS. Fathers had a significant association with their TS daughters in Art–Pog (P < 0.01) measurement.
The results suggest that maternal influences contribute to the growth of a distinct cranial base and to the magnitude of mandibular retrognathism of subjects with TS.
中文译文:
摘要：研究目的是评价女性特纳综合征患者及其父母颅面部特征间的关系。采用13个线距及8个角度测量值分析63位女性特纳综合征患者及80位正常家庭成员的头侧位x片。女性特纳综合征患者与其母亲(n = 41)或与其成年姐妹(n = 27)测量结果的统计学差异反映了特纳综合征患者的颅面部特征。采用回归模型评价女性特纳综合征患者与其父母(n = 41 母亲 及 n = 12 父辈)颅面部特征间的关系。女性特纳综合征患者显著颅面部特征：颅底角增大，前颅底长度减小(S–Ba)，上下颌骨后缩(<SNB )，腭高度降低，关节窝及下颌角点相对于蝶鞍点的长度减小，下颌总长度(Art–Pog)减小，面角增大。患者母亲的S–Ba (P = 0.001)，<SNB (P < 0.001), S–Go (P < 0.01) 及 S–Art (P < 0.05)能够良好预测其女儿的面部相应测量值。患者父亲与女儿的Art–Pog (P < 0.01)有高度相关性。结果表明患者母亲对患者在颅底角的生长情况及下颌后缩的程度有显著影响。
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作者：Perkiomaki MR, Kyrkanides S, Niinimaa A, Alvesalo L.
杂志全名：European Journal of Orthodontics
年份，卷（期），起止页码：2005 Feb;27(1):48-52.
PMID：15743862
英文摘要：
SUMMARY The present study aimed to assess the relationship of craniofacial features between females with Turner syndrome (TS) and their parents. Lateral cephalograms of 63 TS females and 80 family members with normal karyotype were analysed using 13 linear and eight angular cephalometric measurements.The statistical differences of the measurements between adult TS females and their mothers (n = 41)and between adult TS females and their adult sisters (n = 27) were calculated to define the distinct craniofacial features of subjects with TS. Regression models were computed to assess the association of distinct craniofacial features between TS females and their parents (n = 41 for mothers and n = 12 forfathers).
Distinct craniofacial features of the subjects with TS were an increased cranial base flexion, shortened posterior cranial base length (S–Ba), retrognathic maxilla and mandible (<SNB ), shortened distance of the palate, glenoid fossa (S–Art) and gonion (S–Go) from sella, shortened body and total length (Art–Pog)of the mandible and increased vertical angles of the facial skeleton. The mothers’ S–Ba (P = 0.001),<SNB (P < 0.001), S–Go (P < 0.01) and S–Art (P < 0.05) measurements predicted well the corresponding measurements of their daughters with TS. Fathers had a significant association with their TS daughters in Art–Pog (P < 0.01) measurement.
The results suggest that maternal influences contribute to the growth of a distinct cranial base and to the magnitude of mandibular retrognathism of subjects with TS.
中文译文:
摘要：研究目的是评价女性特纳综合征患者及其父母颅面部特征间的关系。采用13个线距及8个角度测量值分析63位女性特纳综合征患者及80位正常家庭成员的头侧位x片。女性特纳综合征患者与其母亲(n = 41)或与其成年姐妹(n = 27)测量结果的统计学差异反映了特纳综合征患者的颅面部特征。采用回归模型评价女性特纳综合征患者与其父母(n = 41 母亲 及 n = 12 父辈)颅面部特征间的关系。女性特纳综合征患者显著颅面部特征：颅底角增大，前颅底长度减小(S–Ba)，上下颌骨后缩(<SNB )，腭高度降低，关节窝及下颌角点相对于蝶鞍点的长度减小，下颌总长度(Art–Pog)减小，面角增大。患者母亲的S–Ba (P = 0.001)，<SNB (P < 0.001), S–Go (P < 0.01) 及 S–Art (P < 0.05)能够良好预测其女儿的面部相应测量值。患者父亲与女儿的Art–Pog (P < 0.01)有高度相关性。结果表明患者母亲对患者在颅底角的生长情况及下颌后缩的程度有显著影响。
=====================================================================
版权声明：本文文字内容归丁香园网站（ http://www.dxy.cn ）及本人所有，未经网站书面许可，请勿转载或摘编
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