【资源】Bacterial Biofilms (Current Topics in Microbiology and Immunology)2008

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By Tony Romeo

Publisher: Springer

Number Of Pages: 308

Publication Date: 2008-04

Throughout the biological world, bacteria thrive predominantly in surface attached, matrix enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiologyspeciesnutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. , but there are also commonalities. In most species, environmental and and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the de******ive stage, and have begun to provide molecular details of the structural, biochemical and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various

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