【摘要翻译】健康儿童尿液生成，尿垂体后叶素及前列腺素E2分泌的昼夜节律
发布于 2004-06-03 · 浏览 756 · IP 陕西陕西
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文题：THE CIRCADIAN RHYTHM OF URINE PRODUCTION, AND URINARY VASOPRESSIN AND PROSTAGLANDIN E2 EXCRETION IN HEALTHY CHILDREN.
健康儿童尿液生成，尿垂体后叶素及前列腺素E2分泌的昼夜节律
作者：KAMPERIS, KONSTANTINOS; HANSEN, MARTIN N.; HAGSTROEM, SOREN; HVISTENDAHL, GITTE; DJURHUUS, JENS C.; RITTIG, SOREN
杂志全名： Journal of Urology
年份，卷（期）: 起止页码： 171(6, Part 2 of 2):2571-2575, June 2004
PMID：
英文摘要：
Purpose: In adults and adolescents the transition from day to night is followed by a pronounced decrease in diuresis, as well as reduction in the amount of osmotically active substances excreted. We investigate the circadian variations in urine production in healthy children 3 to 14 years old.
Materials and Methods: A total of 92 children completed urine collections in 2 consecutive days to be analyzed for electrolytes, urea, creatinine, osmolality, vasopressin and prostaglandin E2.
Results: We found a marked reduction in urine output during the night (43.41 18.53 to 25.69 12.71 ml per hour) accompanied by a decrease in the amount of electrolytes excreted (sodium 4.44 2.09 to 2.66 1.55 mmol per hour and potassium 2.38 0.96 to 0.90 0.54 mmol per hour). Age and gender did not influence the observed circadian rhythm in the quantity and quality of urine production. Urinary excretion of vasopressin did not seem to reflect the circadian variations previously described for the plasma levels of the hormone. Prostaglandin E2 showed a clear circadian variation with a 30% decrease at night (32.2 19.0 to 22.0 12.6 ng/mmol creatinine).
Conclusions: Healthy children exhibit pronounced circadian variations in the amount and composition of urine output with a decrease in nocturnal diuresis and excretion of osmotically active solutes. In the age range of 3 to 14 years neither age nor gender seems to affect this rhythm. Vasopressin-to-prostaglandin E2 excretion ratio appears to be of importance for regulation of urine production.
中文译文：目的：成人和青少年从白天到夜晚其尿量减少，同时产生渗透压的物质分泌减少。我们则研究了3-14岁健康儿童尿液生成的昼夜节律。
材料与方法：收集共92名儿童的连续2天的尿液进行电解质、尿素、肌酐、渗透压、垂体后叶素和前列腺E2测定。
结果：我们发现夜间尿液的生成相对于白天明显减少（43.41±18.53ml/h相对于25.69±12.71ml/h），同时，电解质的分泌量也明显减少（钠，4.44±2.09mmol/h相对于2.66±1.55mmol/h，钾2.38±0.96mmol/h相对于0.90±0.54mmol/h）。年龄和性别对观察到的尿液的质和量的昼夜节律没有影响。尿垂体后叶素并不反映以前描述的血浆激素水平的昼夜节律变化。前列腺素E2显示明显的昼夜节律，夜晚较白天降低大约30%（32.2±19.0相对于22.0±12.6ng/mmol肌酐）。
结论：健康儿童尿液的成分和量具有明显的昼夜节律，夜间尿量和和产生渗透压的物质分泌减少。在3-14岁年龄段内，年龄和性别不影响这种节律。垂体后叶素-前列腺素E2比率对尿液生成调节具有重要作用。
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个人评论：感觉这文章也不难么，没有检索有没有类似的文章，不过从摘要看，似乎是一个系列中的一篇。
健康儿童尿液生成，尿垂体后叶素及前列腺素E2分泌的昼夜节律
作者：KAMPERIS, KONSTANTINOS; HANSEN, MARTIN N.; HAGSTROEM, SOREN; HVISTENDAHL, GITTE; DJURHUUS, JENS C.; RITTIG, SOREN
杂志全名： Journal of Urology
年份，卷（期）: 起止页码： 171(6, Part 2 of 2):2571-2575, June 2004
PMID：
英文摘要：
Purpose: In adults and adolescents the transition from day to night is followed by a pronounced decrease in diuresis, as well as reduction in the amount of osmotically active substances excreted. We investigate the circadian variations in urine production in healthy children 3 to 14 years old.
Materials and Methods: A total of 92 children completed urine collections in 2 consecutive days to be analyzed for electrolytes, urea, creatinine, osmolality, vasopressin and prostaglandin E2.
Results: We found a marked reduction in urine output during the night (43.41 18.53 to 25.69 12.71 ml per hour) accompanied by a decrease in the amount of electrolytes excreted (sodium 4.44 2.09 to 2.66 1.55 mmol per hour and potassium 2.38 0.96 to 0.90 0.54 mmol per hour). Age and gender did not influence the observed circadian rhythm in the quantity and quality of urine production. Urinary excretion of vasopressin did not seem to reflect the circadian variations previously described for the plasma levels of the hormone. Prostaglandin E2 showed a clear circadian variation with a 30% decrease at night (32.2 19.0 to 22.0 12.6 ng/mmol creatinine).
Conclusions: Healthy children exhibit pronounced circadian variations in the amount and composition of urine output with a decrease in nocturnal diuresis and excretion of osmotically active solutes. In the age range of 3 to 14 years neither age nor gender seems to affect this rhythm. Vasopressin-to-prostaglandin E2 excretion ratio appears to be of importance for regulation of urine production.
中文译文：目的：成人和青少年从白天到夜晚其尿量减少，同时产生渗透压的物质分泌减少。我们则研究了3-14岁健康儿童尿液生成的昼夜节律。
材料与方法：收集共92名儿童的连续2天的尿液进行电解质、尿素、肌酐、渗透压、垂体后叶素和前列腺E2测定。
结果：我们发现夜间尿液的生成相对于白天明显减少（43.41±18.53ml/h相对于25.69±12.71ml/h），同时，电解质的分泌量也明显减少（钠，4.44±2.09mmol/h相对于2.66±1.55mmol/h，钾2.38±0.96mmol/h相对于0.90±0.54mmol/h）。年龄和性别对观察到的尿液的质和量的昼夜节律没有影响。尿垂体后叶素并不反映以前描述的血浆激素水平的昼夜节律变化。前列腺素E2显示明显的昼夜节律，夜晚较白天降低大约30%（32.2±19.0相对于22.0±12.6ng/mmol肌酐）。
结论：健康儿童尿液的成分和量具有明显的昼夜节律，夜间尿量和和产生渗透压的物质分泌减少。在3-14岁年龄段内，年龄和性别不影响这种节律。垂体后叶素-前列腺素E2比率对尿液生成调节具有重要作用。
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个人评论：感觉这文章也不难么，没有检索有没有类似的文章，不过从摘要看，似乎是一个系列中的一篇。
最后编辑于 2004-06-20 · 浏览 756
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