【求助】哪位高手能否帮我翻译一小段关于美罗华的英文?
B lymphocytes have been shown to react with many self antigens. There is also evidence that some autoantibodies may drive their own production. It has been suggested in studies of RA that a subset of rheumatoid factors may stimulate the survival of B lymphcytes producing the same autoantibodies. Agents that exclusively target B cells might therefore disrupt autoantibody production. However, despite effective elimination of nearly all peripheral CD20 positive B lymphocytes lymphocytes by rituximab, the total levels of serum IgG and IgA immunoglobulins remain unchanged for prolonged periods, with only moderate and early declines in IgM. Therefore, the exact mechanism by which rituximab interferes with the full spectrum of B cell autoimmunity is still not known.