各位大虾，小弟第一次碰到这种情况，下一步修改后接受的机会还大吗？

编辑及审稿人意见：

Thank you for submitting your manuscript "###" to the International Journal of Cancer. Our reviewing process has now been completed by three outside experts and by the Editors. The reviewers have raised some important concerns about the paper and, after careful consideration of the points made, we regret to conclude that your manuscript is not suitable for publication in IJC in its present form. Our decision is based on the lower priority of the work in light of current competition it faces and our stringent criteria for publication. We hope that you find the reviews helpful.  If you are able to rewrite the manuscript according to the specific criticisms of the reviewers, you can resubmit it as a new paper using our online system. If you choose to resubmit, please indicate the changes you have made, point by point, in a cover letter and highlight them in the revised paper. This will be helpful for reevaluation of your paper.

Thank you for considering IJC for the publication of your manuscript and for your interest in the Journal.  Sincerely,

Prof. Peter Lichter Editor-in-Chief, International Journal of Cancer

Reviewer Comments

Reviewer: 1  Comments to Author

The authors should be complimented for arranging this large collaborative effort that resulted in a large study size--adequate for investigating the question.  巴拉巴拉让补充一个分析表格.  

Reviewer: 2  Comments to Author

This study described that 。。。. The results seem interesting, however, the number of patients was small, and the difference was weak. I have some concerns as below：巴拉巴拉提了四条意见，个人觉得2个不难回答，另外2个审稿人可能真没仔细看文章。

Reviewer: 3  Comments to Author The paper is a very good study. Few points to consider：巴拉巴拉添加几个指标，修改语言之类的。。。