【medical-news】家庭血压和办公室血压是普通人群心血管病风险的强预测因子
18 July 2007
MedWire News: Both home blood pressure (HBP) and office BP (OBP) are significant predictors of cardiovascular (CV) risk in the general population, Greek researchers report.
HBP is increasingly being used in clinical practice, but no extra prognostic value of this measure was found in the current study, report George Stergiou (Sotiria Hospital, Athens) and colleagues.
The team invited all adults living in the Didima area in Greece to participate in a cross-sectional study involving two visits to their doctor’s office for OBP measurements to be taken, and HBP measurement on 3 days.
A total of 662 individuals, with a mean age of 54 years, participated. During an average 8.2-year follow-up, 78 deaths, of which 42 had a CV cause, and 67 CV events occurred.
The unadjusted hazard ratios (HR) for CV events per 1 mmHg increase in systolic HBP and diastolic HBP were 1.034 (p<0.001) and 1.037 (p<0.01), respectively. The corresponding HRs for OBP were 1.035 (p<0.001) and 1.021 (p=0.07).
After adjustment for all available CV risk predictors, only diastolic OBP remained a significant predictor for CV events, however. And the addition of HBP did not significantly improve the predictive ability of the risk model including OBP, which the authors say is in contrast to previous study findings.
The authors conclude that the study “adds to the evidence showing that HBP has strong prognostic value.”
They comment that the available evidence for the prognostic value of HBP is still weak because all except one published outcome studies have been based on relatively small numbers of events.
“Thus more and larger studies are needed, particularly for the assessment of the prognostic value of white-coat and masked hypertension phenomena detected by HBP monitoring,” Stergiou et al write in the Journal of Hypertension.
J Hypertens 2007; 25: 1590-1596
http://www.incirculation.net/NewsItem/Home-and-office-BP-predict-CV-risk-in-general-popu.aspx
最后编辑于 2022-10-09 · 浏览 1587