Wernicke encephalopathy is often underrecognized, with estimates suggesting that only about 15% of cases of WE are diagnosed before death. Alcoholism is the most common predisposing factor in the US. What other patient groups are at risk for WE?
WE occurs in patients with nutritional deficiency, e.g. hyperemesis gravidarum, intestinal obstruction, bariatric surgery, cancer chemotherapy, and hemodialysis. WE can occur in children, with most cases due to malignancy ()