"Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights         the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on         quality by design (QbD) concepts. It covers all important issues by way of case studies,         ranging from properties and crystallization, via thermodynamics, analytics and theoretical         modelling right up to patent issues.
As such, the book underscores the importance         of solid-state chemistry within chemical and pharmaceutical development. It emphasizes         why solid-state issues are important, the approaches needed to avoid problems and         the opportunities offered by solid-state properties. The authors include true polymorphs         as well as solvates and hydrates, while providing information on physicochemical properties,         crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important         analytical tools to characterize solid-state forms and to quantify mixtures are summarized,         and case studies on solid-state development processes in industry are also provided.          
Written by acknowledged experts in the field, this is a high-quality reference         for researchers, project managers and quality assurance managers in pharmaceutical,         agrochemical and fine chemical companies as well as for academics and newcomers to         organic solid-state chemistry

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