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【资讯翻译】跑步并不会导致膝关节炎而是阻止其发生

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原文链接：http://www.newswise.com/articles/running-does-not-lead-to-knee-osteoarthritis-and-may-protect-people-from-developing-the-disease?ret=/articles/list&channel=&category=latest&page=11&search[status]=3&search[sort]=date+desc&search[has_multimedia]=
Running Does Not Lead to Knee Osteoarthritis and May Protect People From Developing the Disease
Running as a habitual exercise at any stage in life not only does not increase a person’s risk of developing knee osteoarthritis and may even help protect a person from developing the painful disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in Boston.
Osteoarthritis, or OA, is the most common joint disease affecting middle-age and older people. It is characterized by progressive damage to the joint cartilage—the cushioning material at the end of long bones—and causes changes in the structures around the joint. These changes can include fluid accumulation, bony overgrowth, and loosening and weakness of muscles and tendons, all of which may limit movement and cause pain and swelling.
Knee osteoarthritis is a common form of OA and is caused by cartilage breakdown in the knee joint. Factors that can increase the risk of knee osteoarthritis include: being overweight, age, injury or stress to the joints and having a family history.
Past research on a possible connection between running and knee OA has focused on elite male runners, so those findings may not apply well to the general population, the study’s authors noted. Concern that regular running might contribute to knee OA focuses on the fact that chronic, mechanical overloading of the knee joints might be damaging. Yet runners typically have a lower body mass index, or BMI, a factor that protects against developing knee OA.
“Recent CDC guidelines recommend that all adults participate in regular physical activity, as there is definitive evidence that increased physical activity is associated with reduced cardiovascular events and mortality,” said Grace Hsiao-Wei Lo, MD, MSc of Baylor College of Medicine and a lead author of the study. “However, the influence of these physical activities on knee OA is unclear. Since running is a common leisure physical activity that involves repetitive loading, which could be harmful to the joint, I was particularly interested in studying how habitual running relates to the development of knee OA.”
To find out if habitual running would increase knee OA risk for the general population, the researchers used data from a multicenter observational study, the Osteoarthritis Initiative (OAI). Of the 2,683 participants, 56 percent were female, the mean age was 64.5 and the mean BMI was 28.6. Twenty-nine percent of the participants reported that they ran at some time in their lives.
Patients had knee X-rays, were given symptom assessments, and were asked to complete the Lifetime Physical Activity Questionnaire (LPAQ), identifying the top three most frequently performed physical activities (≥ 10 times in life) they performed at different age ranges throughout their life. Age ranges included 12-18, 19-34, 35-49, and 50 years or older.
At the OAI 48-month visit, knee X-rays were taken and then scored for evidence of radiographic OA using the Kellgren-Lawrence (KL) grade scale. Participants with KL grades of two or higher were considered as having radiographic OA (ROA). The researchers also measured if participants had frequent knee pain at their 48-month visit. Researchers considered a participant to have symptomatic OA (SOA) if they had at least one knee with both ROA and frequent knee pain. Anyone with a total knee replacement was classified as having frequent knee pain, ROA and SOA.
After collecting all the data, the researchers reported that runners, regardless of the age when they ran, had a lower prevalence of knee pain, ROA and SOA than non-runners. For people who had run at any time in their lives, 22.8 percent had SOA compared to 29.8 percent of non-runners. People with the lowest BMI scores were the most likely to report being habitual runners. Regular running, even at a non-elite level, not only does not increase the risk of developing knee OA but may protect against it, the researchers concluded.
“This does not address the question of whether or not running is harmful to people who have pre-existing knee OA,” said Dr. Lo. “However, in people who do not have knee OA, there is no reason to restrict participation in habitual running at any time in life from the perspective that it does not appear to be harmful to the knee joint.”
Funding sources for this study included National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health; the Center for Innovations in Quality, Effectiveness and Safety; and the Michael E. DeBakey VA Medical Center in Houston.

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2014-11-18 12:42 浏览 : 1890 回复 : 14

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2014-11-18 12:49 来自 Android客户端

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Running Does Not Lead to KneeOsteoarthritis and May Protect People From Developing the Disease
跑步并不会导致膝骨性关节炎且可能防止患此疾病
1.Running as a habitual exercise at anystage in life not only does not increase a person’s risk of developing kneeosteoarthritis and may even help protect a person from developing the painfuldisease, according to new research findings presented this week at the American Collegeof Rheumatology Annual Meeting in Boston.
根据本周在波士顿举办的美国风湿协会上展示的新研究成果，作为一个生活中惯常的锻炼，跑步不仅不会增加患膝骨关节炎的风险，甚至可能会帮助防止患这个令人痛苦的疾病。
2.Osteoarthritis, or OA, is the most commonjoint disease affecting middle-age and older people. It is characterized byprogressive damage to the joint cartilage—the cushioning material at the end oflong bones—and causes changes in the structures around the joint. These changescan include fluid accumulation, bony overgrowth, and loosening and weakness ofmuscles and tendons, all of which may limit movement and cause pain andswelling.
骨关节炎，或OA，是困扰中老年人最常见的关节疾病。其特点为渐进性的关节软骨（长骨末端有缓冲作用的组织）损害及关节周围结构的改变。这些改变可能包括积液、骨赘及肌肉和肌腱松弛及萎缩，以上改变均可能导致活动受限、疼痛及肿胀。
3.Knee osteoarthritis is a common form ofOA and is caused by cartilage breakdown in the knee joint. Factors that canincrease the risk of knee osteoarthritis include: being overweight, age, injuryor stress to the joints and having a family history.
膝骨关节炎是OA的一种常见形式，由膝关节软骨的破坏引起。可能增加膝骨关节炎风险的因素包括：肥胖、高龄、关节损伤或应激及家族史。
4.Past research on a possible connectionbetween running and knee OA has focused on elite male runners, so thosefindings may not apply well to the general population, the study’s authorsnoted. Concern that regular running might contribute to knee OA focuses on thefact that chronic, mechanical overloading of the knee joints might be damaging.Yet runners typically have a lower body mass index, or BMI, a factor thatprotects against developing knee OA.
过去关于跑步和膝骨关节炎之间可能的联系的研究主要集中于精英男跑步运动员，因此那些结果可能不很适用于一般人群，该研究的作者提到。考虑到规律的跑步可能会导致膝骨关节炎是基于慢性、机械性膝关节超负荷可能会（造成）损害这一事实。然而，跑步运动员代表性地有低体重指数或称BMI—一个针对膝骨关节炎的保护性因素。
5.“Recent CDC guidelines recommend that alladults participate in regular physical activity, as there is definitiveevidence that increased physical activity is associated with reducedcardiovascular events and mortality,” said Grace Hsiao-Wei Lo, MD, MSc ofBaylor College of Medicine and a lead author of the study. “However, theinfluence of these physical activities on knee OA is unclear. Since running isa common leisure physical activity that involves repetitive loading, whichcould be harmful to the joint, I was particularly interested in studying howhabitual running relates to the development of knee OA.”
“最近的CDC指南建议所有的成年人参加规律的体育活动，因为有明确的证据（指出）：体育活动的增加和心血管事件及死亡率的减少相关”，该研究的第一作者、贝勒大学医学院GraceHsiao-Wei Lo（MD, MSc，）说：“……。因为跑步是一种涉及到可能对关节有害的负荷反复加载的常见业余体育活动，所以我对研究习惯性跑步如何与膝骨关节炎的发展相关很感兴趣。”
6.Tofind out if habitual running would increase knee OA risk for the generalpopulation, the researchers used data from a multicenter observational study,the Osteoarthritis Initiative (OAI). Of the 2,683 participants, 56 percent werefemale, the mean age was 64.5 and the mean BMI was 28.6. Twenty-nine percent ofthe participants reported that they ran at some time in their lives.
为查明是否习惯性跑步会增加一般人群患膝骨关节炎的风险，研究者应用了来自一项多中心观察研究项目“骨关节炎倡议（OsteoarthritisInitiative，OAI）”的数据。在2,683名受试者中，56%为女性，平均年龄64.5岁，平均BMI 28.6。29%的受试者报告他们在生活中某些时间会跑步。
7.Patients had knee X-rays, were givensymptom assessments, and were asked to complete the Lifetime Physical ActivityQuestionnaire (LPAQ), identifying the top three most frequently performedphysical activities (≥ 10 times in life) they performed at different age ranges throughouttheir life. Age ranges included 12-18, 19-34, 35-49, and 50 years or older.
做了膝关节X线片检查的病人被做了症状评估，并被要求完成终身体育活动调查问卷（LPAQ），以确认他们在一生中不同年龄段所做的3个最频繁的体育活动（≥10次）。年龄段包括12-18岁、19-34岁、35-49岁和50岁及以上。
8.At the OAI 48-month visit, knee X-rayswere taken and then scored for evidence of radiographic OA using theKellgren-Lawrence (KL) grade scale. Participants with KL grades of two orhigher were considered as having radiographic OA (ROA). The researchers alsomeasured if participants had frequent knee pain at their 48-month visit.Researchers considered a participant to have symptomatic OA (SOA) if they hadat least one knee with both ROA and frequent knee pain. Anyone with a totalknee replacement was classified as having frequent knee pain, ROA and SOA.
在第48个月的OAI随诊时，做膝关节X线片后用Kellgren-Lawrence（KL）分级标准为骨关节炎的放射线证据评分。KL积分大于2分或更高的受试者被视为患有放射线表现上的膝骨关节炎（ROA）。研究者也检查受试者在他们第48个月随诊时是否有频繁的膝痛。如果受试者至少一个膝部有ROA且频繁膝痛，研究者视为有症状的膝关节炎（SOA）。任何有全膝关节置换的人均被分为频繁膝关节疼痛、ROA及SOA。
9.After collecting all the data, theresearchers reported that runners, regardless of the age when they ran, had alower prevalence of knee pain, ROA and SOA than non-runners. For people who hadrun at any time in their lives, 22.8 percent had SOA compared to 29.8 percentof non-runners. People with the lowest BMI scores were the most likely toreport being habitual runners. Regular running, even at a non-elite level, notonly does not increase the risk of developing knee OA but may protect againstit, the researchers concluded
收集所有数据后，研究者报告说，跑步者（无论其跑步的年龄如何）较不跑步者的膝痛、ROA及SOA的患病率低。对在一生中任何时间段跑步的人，与不跑跑步者的29.9%相比有22.8%患SOA。BMI分数最低的人最有可能报告是习惯性跑步者。研究者得出这样的结论：规律的跑步，即便是不优秀的水平，不仅不会增加患膝骨关节炎的风险，反而可能保护膝关节。
10.“This does not address the question ofwhether or not running is harmful to people who have pre-existing knee OA,”said Dr. Lo. “However, in people who do not have knee OA, there is no reason torestrict participation in habitual running at any time in life from theperspective that it does not appear to be harmful to the knee joint.”
“这并未提到跑步对已有膝骨关节炎的人是否有害的问题”Dr. Lo.说，“然而在未患膝骨关节炎的人中，从跑步并未表现出对膝关节有害的角度来说，没有理由限制参加一生中任何时间惯常的跑步”
11.Funding sources for this study includedNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)of the National Institutes of Health; the Center for Innovations in Quality,Effectiveness and Safety; and the Michael E. DeBakey VA Medical Center in Houston.
该研究的筹资来源包括国立卫生研究院的国家关节炎和肌肉骨骼及皮肤病研究所（NIAMS），质量、有效性和安全性创新中心及休斯顿Michael E. DeBakey VA医学中心。

2014-11-19 11:38

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雪航妹纸编辑于 2015-01-23 14:11

• 健康管理师相关资料汇总

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跑步并不会导致膝骨性关节炎且可能防止患此疾病
根据本周在波士顿举办的美国风湿协会上展示的新研究成果，作为一个生活中惯常的锻炼，跑步不仅不会增加患膝骨关节炎的风险，甚至可能会帮助防止患这个令人痛苦的疾病。
骨关节炎，或OA，是困扰中老年人最常见的关节疾病。其特点为渐进性的关节软骨（长骨末端有缓冲作用的组织）损害及关节周围结构的改变。这些改变可能包括积液、骨赘及肌肉和肌腱松弛及萎缩，以上改变均可能导致活动受限、疼痛及肿胀。
膝骨关节炎是OA的一种常见形式，由膝关节软骨的破坏引起。可能增加膝骨关节炎风险的因素包括：肥胖、高龄、关节损伤或应激及家族史。
过去关于跑步和膝骨关节炎之间可能的联系的研究主要集中于精英男跑步运动员，因此那些结果可能不很适用于一般人群，该研究的作者提到。考虑到规律的跑步可能会导致膝骨关节炎是基于慢性、机械性膝关节超负荷可能会（造成）损害这一事实。然而，跑步运动员代表性地有低体重指数或称BMI—一个针对膝骨关节炎的保护性因素。
“最近的CDC指南建议所有的成年人参加规律的体育活动，因为有明确的证据（指出）：体育活动的增加和心血管事件及死亡率的减少相关”，该研究的第一作者、贝勒大学医学院GraceHsiao-Wei Lo（MD, MSc，）说：“……。因为跑步是一种涉及到可能对关节有害的负荷反复加载的常见业余体育活动，所以我对研究习惯性跑步如何与膝骨关节炎的发展相关很感兴趣。”
为查明是否习惯性跑步会增加一般人群患膝骨关节炎的风险，研究者应用了来自一项多中心观察研究项目“骨关节炎倡议（OsteoarthritisInitiative，OAI）”的数据。在2,683名受试者中，56%为女性，平均年龄64.5岁，平均BMI 28.6。29%的受试者报告他们在生活中某些时间会跑步。
做了膝关节X线片检查的病人被做了症状评估，并被要求完成终身体育活动调查问卷（LPAQ），以确认他们在一生中不同年龄段所做的3个最频繁的体育活动（≥10次）。年龄段包括12-18岁、19-34岁、35-49岁和50岁及以上。
在第48个月的OAI随诊时，做膝关节X线片后用Kellgren-Lawrence（KL）分级标准为骨关节炎的放射线证据评分。KL积分大于2分或更高的受试者被视为患有放射线表现上的膝骨关节炎（ROA）。研究者也检查受试者在他们第48个月随诊时是否有频繁的膝痛。如果受试者至少一个膝部有ROA且频繁膝痛，研究者视为有症状的膝关节炎（SOA）。任何有全膝关节置换的人均被分为频繁膝关节疼痛、ROA及SOA。
收集所有数据后，研究者报告说，跑步者（无论其跑步的年龄如何）较不跑步者的膝痛、ROA及SOA的患病率低。对在一生中任何时间段跑步的人，与不跑跑步者的29.9%相比有22.8%患SOA。BMI分数最低的人最有可能报告是习惯性跑步者。研究者得出这样的结论：规律的跑步，即便是不优秀的水平，不仅不会增加患膝骨关节炎的风险，反而可能保护膝关节。
“这并未提到跑步对已有膝骨关节炎的人是否有害的问题”Dr. Lo.说，“然而在未患膝骨关节炎的人中，从跑步并未表现出对膝关节有害的角度来说，没有理由限制参加一生中任何时间惯常的跑步”
该研究的筹资来源包括国立卫生研究院的国家关节炎和肌肉骨骼及皮肤病研究所（NIAMS），质量、有效性和安全性创新中心及休斯顿Michael E. DeBakey VA医学中心。

2014-11-19 19:55

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雪航妹纸编辑于 2015-01-23 14:14

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