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【medical-news】新治疗减轻骨痛延长前列腺癌病人生存

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New Treatment Reduces Bone Pain, Extends Survival in Prostate Cancer Patients
Prostate cancer that has spread to the bones can cause pain and fractures.
Loyola University Medical Center is among the first hospitals in Chicago to offer a new targeted radiation treatment that can reduce bone pain and the incidence of fractures – and also extend patients’ lives.
The treatment, recently approved by the Food and Drug Administration, is called Xofigo®. A radioactive substance, radium-223, is injected into the patient. Because it is similar to calcium, radium-223 binds to the bone. Radium-223 delivers high-energy radiation over a short distance, providing a targeted treatment that is less damaging to other structures or tissues, said Robert Wagner, MD, medical director of Nuclear Medicine in Loyola’s Department of Radiology.
Radium-223 is rapidly cleared from the blood stream. Fifteen minutes after injection, about 20 percent of the injected radioactivity remains in the blood. By 24 hours, less than 1 percent of radioactivity remains.
Xofigo is indicated for prostate cancer patients in which:
-  the cancer has spread to the bones, but not to other organs
-  the cancer is not responding to hormone therapy or surgery that blocks production of testosterone, and
-  the cancer spread to the bones is causing other serious symptoms.
Radium-223 is injected into an IV line in a patient’s vein, in a procedure that takes less than 5 minutes. The patient receives a series of six injections, given once every four to six weeks.
Side effects can include upset stomach, diarrhea, swelling in the hands and feet and decreased counts of red blood cells, white blood cells and platelets.
“While the treatment is not a cure, it can enable patients to live longer, with significantly improved quality of life,” Wagner said.

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2013-08-23 19:37 浏览 : 413 回复 : 1

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Prostate cancer that has spread to thebones can cause pain and fractures.
前列腺癌扩散到骨头可引起疼痛和骨折。
Loyola UniversityMedical Center is among the first hospitals in Chicago to offer a new targetedradiation treatment that can reduce bone pain and the incidence of fractures –and also extend patients’ lives.
洛约拉大学医学中心是芝加哥首批提供新的靶向放射治疗的医院，新的放射治疗可以减少骨痛和骨折的发生率-也可延长患者的生命。
The treatment, recentlyapproved by the Food and Drug Administration, is called Xofigo®. Aradioactive substance, radium-223, is injected into the patient. Because it issimilar to calcium, radium-223 binds to the bone. Radium-223 delivershigh-energy radiation over a short distance, providing a targeted treatmentthat is less damaging to other structures or tissues, said Robert Wagner, MD,medical director of Nuclear Medicine in Loyola’s Department of Radiology.
这种被称为Xofigo的治疗，最近已被FDA批准。放射性物质镭223注射到患者体内。因为与钙类似，镭223可与骨结合。镭223在很短距离可提供高能量的辐射，从而提供有针对性的治疗并且对其他结构或组织有较小的损伤。洛约拉放射科核医学内科主任医师罗伯特·瓦格纳说。

Radium-223 is rapidlycleared from the blood stream. Fifteen minutes after injection, about 20percent of the injected radioactivity remains in the blood. By 24 hours, lessthan 1 percent of radioactivity remains.
镭223在血液中可迅速被清除。注射15分钟后，大约20％的放射物质残留在血液中。到24小时，只有不到1％的放射性物质残留。
Xofigo is indicated forprostate cancer patients in which:
Xofigo对前列腺癌患者的启示：
- the cancerhas spread to the bones, but not to other organs
- the canceris not responding to hormone therapy or surgery that blocks production oftestosterone,
- the cancerspread to the bones is causing other serious symptoms.
-肿瘤已经扩散到骨头，而不是其他器官
- 肿瘤对激素和手术治疗没有反应而是抑制睾酮的产生
- 肿瘤扩散到骨头引起其它严重的症状。

Radium-223 is injectedinto an IV line in a patient’s vein, in a procedure that takes less than 5minutes. The patient receives a series of six injections, given once every fourto six weeks.

在少于5分钟的过程中，镭223注入到病人的静脉中。病人需要接受6次连续注射，每4至6周1次。
第一次发翻译的，练下手，请多多指教！

版主lightningwing留言:
请战友认领前注意有资讯翻译字样的帖子才能认领

2013-08-25 19:38

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lightningwing 编辑于 2013-08-25 22:26

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